Etoposide Impurity 35 CAS CATO-C4X-202435
| CAS No. | CATO-C4X-202435 |
| Molecular Formula | C12H14Cl4O8 |
| Molecular Weight | 428.05 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Etoposide Impurity 35.
CATO supplies Etoposide Impurity 35 (CAS CATO-C4X-202435), a pharmacopoeial impurity reference standard (molecular formula C12H14Cl4O8, MW 428.05 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Etoposide Impurity 35 (C12H14Cl4O8) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 428.05 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14Cl4O8 |
| Molecular Weight | 428.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Etoposide Standards
- Etoposide Impurity 25 (CAS CATO-C4X-202425)
- Etoposide Impurity 38 (CAS CATO-C4X-202438)
- Etoposide Impurity 31 (CAS CATO-C4X-202431)
- Etoposide EP Impurity H (CAS 102306-95-6)
- Etoposide EP Impurity J (CAS 118356-05-1)
- Etoposide EP Impurity M (CAS 518-28-5)
- Etoposide EP Impurity L (CAS 40505-27-9)
- Etoposide Impurity 29 (CAS CATO-C4X-202429)
Recommended Standards
- (4aR,6R,7R,8S,8aR)-6-Hydroxy-2-methylhexahydropyrano[3,2-d][1,3]dioxine-7,8-diyl bis(2,2-Dichloroacetate) (CAS 149403-65-6)
- (2E)-3-(3-Bromophenyl)-N-(3-iodophenyl)prop-2-enamide (CAS 882079-32-5)
- 1,5-Diamino-2,6-dibromo-4,8-dihydroxyanthracene-9,10-dione (CAS 30787-41-8)
- 8-Bromo-7-(4-bromobenzyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione (CAS 255730-99-5)
- Amiodarone Impurity 13 (CAS 83790-87-8)
- Atazanavir Impurity 13 (CAS 98760-08-8)
- Tenofovir disoproxil Impurity 143 (CAS CATO-C4X-1076143)
- tert-Butyl 2-(((5-chloropyrimidin-2-yl)oxy)methyl)pyrrolidine-1-carboxylate (CAS 1261232-15-8)
- Evocalcet Impurity 8 (CAS CATO-C4X-24858)
- Rosuvastatin Impurity 261 (CAS CATO-C4X-1169261)
- 2-Cyclopropyl-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one (CAS 1554534-71-2)
- 2-(Difluoromethyl)-3-nitro-4-(trifluoromethoxy)pyridine-5-carboxylic acid (CAS 1806049-12-6)
- (2-(2-Bromoethoxy)ethoxy)(tert-butyl)dimethylsilane (CAS 151556-43-3)
- Anxiety Peptide (CAS 95237-86-8)
Why CATO?
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com