Doxorubicin Impurity 35 CAS CATO-C4X-203335

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-203335
Molecular FormulaC19H12O6
Molecular Weight336.29 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Doxorubicin Impurity 35 CAS CATO-C4X-203335 chemical structure

Description

As a certified reference material (CRM), Doxorubicin Impurity 35 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

As a process- or degradation-related impurity, Doxorubicin Impurity 35 (CAS CATO-C4X-203335, C19H12O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Doxorubicin Impurity 35 (C19H12O6) contains a flavonoid core, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Physical & Chemical Properties

Molecular FormulaC19H12O6
Molecular Weight336.29 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)14.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present

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