Osimertinib Impurity 107 CAS CATO-C4X-2045107
| CAS No. | CATO-C4X-2045107 |
| Molecular Formula | C18H23N5 |
| Molecular Weight | 309.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Osimertinib Impurity 107 (CAS CATO-C4X-2045107, C18H23N5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C18H23N5, Osimertinib Impurity 107 contains a nitrogen-containing heterocyclic scaffold, a nitrile group; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 309.41 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H23N5 |
| Molecular Weight | 309.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Osimertinib Standards
- Osimertinib Impurity 55 (CAS 2364486-24-6)
- Osimertinib Impurity 87 (CAS CATO-C4X-204587)
- Osimertinib Impurity 28 (CAS 6637-11-2)
- Osimertinib Impurity 69 (CAS CATO-C4X-204569)
- Osimertinib Impurity 70 (CAS CATO-C4X-204570)
- Osimertinib Impurity 74 (CAS CATO-C4X-204574)
- Osimertinib Impurity 17 (CAS CATO-C4X-204517)
- Osimertinib Impurity 14 (CAS 2364486-23-5)
Recommended Standards
- Vinpocetine Impurity 2 (Oxime) (CAS 102341-40-2)
- tert-Butyl 4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran]-1-carboxylate (CAS 1283095-48-6)
- Vinpocetine Impurity 30 (CAS CATO-C4X-184330)
- Benzyl 3-(((2-hydroxyethyl)thio)methyl)piperidine-1-carboxylate (CAS 1353945-68-2)
- Flurbiprofen Impurity 149 (CAS CATO-C4X-1444149)
- Nicardipine Impurity 30 (CAS CATO-C4X-171030)
- Difelikefalin Impurity 26 (CAS CATO-C4X-304126)
- 4-(4-Nitrophenyl)pyrimidine (CAS 16495-82-2)
- 1-(6-Bromo-5-methylpyridin-3-yl)-2,2,2-trifluoroethanone (CAS 1402148-94-0)
- methyl 6-vinylnicotinate (CAS 103440-76-2)
- 5-[(3-methylpiperidin-1-yl)methyl]thiophene-2-carboxylic acid (CAS 1174887-28-5)
- [1,1'-Biphenyl]-3,3'-diamine dihydrochloride (CAS 20872-10-0)
- (S)-2-((S)-2-(benzyloxycarbonylamino)propanamido)-3-hydroxypropanoic acid 41864-10-2 Z-Ala-Ser-OH (CAS 41864-10-2)
- Semaglutide impurity 30 (CAS CATO-C4X-222630)
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