Osimertinib Impurity 14 CAS 2364486-23-5
| CAS No. | 2364486-23-5 |
| Molecular Formula | C13H10ClN3 |
| Molecular Weight | 243.69 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Osimertinib Impurity 14 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Osimertinib Impurity 14 (CAS 2364486-23-5, C13H10ClN3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C13H10ClN3, Osimertinib Impurity 14 contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 243.69 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H10ClN3 |
| Molecular Weight | 243.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Osimertinib Standards
- Osimertinib Impurity 15 (CAS 1896788-06-9)
- Osimertinib Impurity 56 (CAS CATO-C4X-204556)
- Osimertinib Impurity 28 (CAS 6637-11-2)
- Osimertinib Impurity 13 (CAS 2090542-75-7)
- Osimertinib Impurity 44 (CAS CATO-C4X-204544)
- Osimertinib Impurity 107 (CAS CATO-C4X-2045107)
- Osimertinib Impurity 111 (CAS 450-84-0)
- Osimertinib Impurity 55 (CAS 2364486-24-6)
Recommended Standards
- Minoxidil Impurity 34 (CAS 2889432-05-5)
- Epalrestat Impurity 52 (CAS CATO-C4X-223652)
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- Tizanidine Impurity 43 (CAS CATO-C4X-144543)
- Pefloxacin Impurity 2 (CAS CATO-C4X-23332)
- Ketorolac Impurity 25 (CAS CATO-C4X-166925)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com