Osimertinib Impurity 76 CAS CATO-C4X-204576
| CAS No. | CATO-C4X-204576 |
| Molecular Formula | C21H21N5O2 |
| Molecular Weight | 375.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Osimertinib Impurity 76.
CATO supplies Osimertinib Impurity 76 (CAS CATO-C4X-204576), a pharmacopoeial impurity reference standard (molecular formula C21H21N5O2, MW 375.42 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C21H21N5O2, Osimertinib Impurity 76 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 375.42 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Osimertinib Impurity 76 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H21N5O2 |
| Molecular Weight | 375.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Osimertinib Standards
- Osimertinib Impurity 77 (CAS CATO-C4X-204577)
- Osimertinib Impurity 17 (CAS CATO-C4X-204517)
- Osimertinib Impurity 89 (CAS CATO-C4X-204589)
- Osimertinib Impurity 36 (CAS CATO-C4X-204536)
- Osimertinib Impurity 53 (CAS CATO-C4X-204553)
- Osimertinib Impurity 74 (CAS CATO-C4X-204574)
- Osimertinib Impurity 69 (CAS CATO-C4X-204569)
- Osimertinib Impurity 70 (CAS CATO-C4X-204570)
Recommended Standards
- Bisacodyl Impurity 16 (CAS CATO-C4X-203716)
- Mivacurium chloride Impurity 48 (CAS CATO-C4X-137548)
- Labetalol Impurity 67 (CAS CATO-C4X-246667)
- Mivacurium chloride Impurity 46 (CAS CATO-C4X-137546)
- Elobixibat Impurity 40 (CAS CATO-C4X-283840)
- Sorafenib Impurity 11 (CAS 1129683-88-0)
- Lasmiditan Impurity 66 (CAS CATO-C4X-247866)
- 3-Oxo-3-(2,4,5-trifluorophenyl)propanenitrile (CAS 142501-42-6)
- Methyl 5-cyano-2-(difluoromethyl)benzoate (CAS 1381846-23-6)
- 914299-83-5 (2R)-2-(2-Methylphenyl)pyrrolidine MFCD06762523 (CAS 914299-83-5)
- (6-(Propylthio)-9H-purin-9-yl)methanol (CAS 14133-08-5)
- Gold, (2-phenylethenyl)(triphenylphosphine)-, (Z)- (CAS 57947-31-6)
- Iguratimod Impurity 53 (CAS CATO-C4X-182653)
- Tirzepatide Impurity 35 (CAS CATO-C4X-324035)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com