Ruxolitinib Impurity 122 CAS CATO-C4X-2058122
| CAS No. | CATO-C4X-2058122 |
| Molecular Formula | C9H13N |
| Molecular Weight | 135.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ruxolitinib Impurity 122.
Ruxolitinib Impurity 122 (CAS CATO-C4X-2058122) is a certified pharmaceutical impurity reference standard with the molecular formula C9H13N and a molecular weight of 135.21 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, Ruxolitinib Impurity 122 is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 135.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ruxolitinib Impurity 122 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H13N |
| Molecular Weight | 135.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Ruxolitinib Standards
- Ruxolitinib Impurity 154 (CAS 1270424-30-0)
- Ruxolitinib Impurity 125 (CAS CATO-C4X-2058125)
- Ruxolitinib Impurity 16 (CAS 28791-95-9)
- Ruxolitinib Impurity 124 (CAS CATO-C4X-2058124)
- Ruxolitinib Impurity 233 (CAS CATO-C4X-2058233)
- Ruxolitinib Impurity 59 (CAS 2802349-76-2)
- Ruxolitinib impurity 227 (CAS 350483-64-6)
- Ruxolitinib Impurity 60 (CAS CATO-C4X-205860)
Recommended Standards
- Indobufen Impurity 36 (CAS 2696-84-6)
- 2,4,5-Trimethylaniline (CAS 137-17-7)
- Dapoxetine Impurity 21 (CAS 2941-20-0)
- 2,4,6-Trimethylaniline (CAS 88-05-1)
- Betamethasone Acetate EP Impurity C (CAS 330157-05-6)
- Isavuconazole impurity 74 (CAS CATO-C4X-1236174)
- Thioctic acid Impurity 87 (CAS CATO-C4X-152687)
- (2,6-Difluoro-3-formylphenyl)boronic acid (CAS 849062-09-5)
- (S,S)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminochromium(III) chloride (CAS 219143-92-7)
- [2-(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)ethyl]amine hydrochloride (CAS 952233-49-7)
- Ethyl 2-cyano-3-ureidoacrylate (CAS 61679-83-2)
- 5-(Aminomethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one (CAS 887405-49-4)
- 8-Fluoronaphthalen-1-amine (CAS 13720-52-0)
- (Ser(PO?H?)3??·???)-Tau Peptide (379-408) trifluoroacetate salt (CAS 2022956-60-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com