Ruxolitinib Impurity 170 CAS CATO-C4X-2058170
| CAS No. | CATO-C4X-2058170 |
| Molecular Formula | C17H20N6O |
| Molecular Weight | 324.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Ruxolitinib Impurity 170 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Ruxolitinib Impurity 170 (CAS CATO-C4X-2058170) is a certified pharmaceutical impurity reference standard with the molecular formula C17H20N6O and a molecular weight of 324.39 g/mol.
The molecular framework of Ruxolitinib Impurity 170 (C17H20N6O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C17H20N6O |
| Molecular Weight | 324.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Ruxolitinib Standards
- Ruxolitinib Impurity 2 (CAS 2102675-42-1)
- Ruxolitinib Impurity 27 (CAS CATO-C4X-205827)
- Ruxolitinib Impurity 6 (CAS 1911644-32-0)
- Ruxolitinib Impurity 169 (CAS CATO-C4X-2058169)
- Ruxolitinib Impurity 3 (CAS 2102675-40-9)
- Ruxolitinib Impurity 77 (CAS 3016399-21-3)
- Ruxolitinib Impurity 1 (CAS 2606144-44-7)
- Ruxolitinib Impurity N7 (Mixture of Diastereomers) (CAS 1092973-95-9)
Recommended Standards
- Citalopram EP Impurity I (Mixture of Z and E Isomers) (CAS CATO-C4X-110918)
- Prusogliptin Impurity 13 (CAS CATO-C4X-328413)
- 5-Bromo-2-chloro-3-iodopyridine 928653-73-0 5-Bromo-2-chloro-3-iodo-pyridine (CAS 928653-73-0)
- Prusogliptin Impurity 14 (CAS CATO-C4X-328414)
- Levetiracetam Impurity 37 (CAS 1847568-87-9)
- Apalutamide Impurity 77 (CAS CATO-C4X-274977)
- Crisaborole impurity 160 (CAS CATO-C4X-2021160)
- 2-(2-Ethoxy-4-formylphenoxy)-N-(1-phenylethyl)acetamide (CAS 881602-71-7)
- 2-(1-Azepanylcarbonyl)benzoic acid 20320-45-0 6856AD C14H17NO3 (CAS 20320-45-0)
- 3a-(Trifluoromethyl)-2,3,3a,4-tetrahydro-1H-benzo[d]pyrrolo[1,2-a]imidazol-1-one (CAS 1191278-87-1)
- 3-(Ethyl(3-methoxyphenyl)amino)propanenitrile (CAS 66188-29-2)
- 6-(Tert-butyl)-4-ethoxynicotinic acid (CAS 1143519-21-4)
- methyl 4-(5-methylthiophen-2-yl)-1H-pyrrole-3-carboxylate (CAS 1803611-72-4)
- Tirzepatide Impurity 43 (CAS CATO-C4X-324043)
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