Ruxolitinib Impurity 21 CAS CATO-C4X-205821

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-205821
Molecular FormulaC25H29N7
Molecular Weight427.54 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Ruxolitinib Impurity 21 CAS CATO-C4X-205821 chemical structure

Description

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

Ruxolitinib Impurity 21 (CAS CATO-C4X-205821) is a certified pharmaceutical impurity reference standard with the molecular formula C25H29N7 and a molecular weight of 427.54 g/mol.

Ruxolitinib Impurity 21 (C25H29N7) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. Its physicochemical properties are representative of its class; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

As a certified reference material (CRM), Ruxolitinib Impurity 21 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC25H29N7
Molecular Weight427.54 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)15.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms7

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