Ruxolitinib Impurity 67 CAS CATO-C4X-205867
| CAS No. | CATO-C4X-205867 |
| Molecular Formula | C22H30N6OSi |
| Molecular Weight | 422.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ruxolitinib Impurity 67.
As a process- or degradation-related impurity, Ruxolitinib Impurity 67 (CAS CATO-C4X-205867, C22H30N6OSi) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Ruxolitinib Impurity 67 (C22H30N6OSi) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Ruxolitinib Impurity 67 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H30N6OSi |
| Molecular Weight | 422.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Ruxolitinib Standards
- Ruxolitinib Impurity 112 (CAS CATO-C4X-2058112)
- Ruxolitinib Impurity 89 (CAS CATO-C4X-205889)
- Ruxolitinib Impurity 20 (CAS CATO-C4X-205820)
- Ruxolitinib Impurity 34 (CAS 1236033-23-0)
- Ruxolitinib Impurity 61 (CAS 1146629-80-2)
- Ruxolitinib Impurity 69 (CAS 1236033-05-8)
- Ruxolitinib Impurity N2 (CAS 191605-10-4)
- Ruxolitinib Impurity 42 (CAS CATO-C4X-205842)
Recommended Standards
- Pregabalin Impurity 62 (CAS CATO-C4X-131262)
- (2S,3S,4S,5R,6S)-6-((5-bromo-6-chloro-1H-indol-3-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid (CAS 144110-42-9)
- Pregabalin Impurity 137 (CAS CATO-C4X-1312137)
- 1,2-Bis(diphenylphosphine)ethane (CAS 1663-45-2)
- Methylprednisolone EP Impurity G (CAS 93269-35-3)
- Landiolol Impurity 13 (CAS 144256-25-7)
- Tadalafil Impurity 108 (CAS CATO-C4X-1087108)
- 4-((1H-Pyrrolo[2,3-b]pyridin-4-yl)oxy)-3-fluoroaniline (CAS 688781-75-1)
- 1-(5-Ethyl-2-furanyl)ethanone (CAS 24119-98-0)
- (3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(3,5-dimethylphenyl)methanone (CAS 898761-91-6)
- (E)-1-(2-chlorophenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one (CAS 1352347-02-4)
- 4-(BEnzyloxy)-2-chloro-1-nitrobenzene (CAS 50545-45-4)
- 4-Carbomethoxy-cyclohexane-1-carboxylic acid (CAS 32529-79-6)
- Liraglutide Impurity 25 (CAS CATO-C4X-199225)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com