Ruxolitinib impurity 52 CAS CATO-C4X-205852
| CAS No. | CATO-C4X-205852 |
| Molecular Formula | C17H19N7O2 |
| Molecular Weight | 353.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 353.38 g/mol gives Ruxolitinib impurity 52 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ruxolitinib impurity 52 (CAS CATO-C4X-205852) is a certified pharmaceutical impurity reference standard with the molecular formula C17H19N7O2 and a molecular weight of 353.38 g/mol.
Ruxolitinib impurity 52 (C17H19N7O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Ruxolitinib impurity 52 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H19N7O2 |
| Molecular Weight | 353.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 7 |
Related Ruxolitinib Standards
- Ruxolitinib Impurity 115 (CAS CATO-C4X-2058115)
- Ruxolitinib Impurity 121 (CAS CATO-C4X-2058121)
- Ruxolitinib Impurity 65 (CAS CATO-C4X-205865)
- Ruxolitinib Impurity 127 (CAS CATO-C4X-2058127)
- Ruxolitinib Impurity 221 (CAS CATO-C4X-2058221)
- Ruxolitinib Impurity 226 (CAS CATO-C4X-2058226)
- Ruxolitinib Impurity 95 (CAS CATO-C4X-205895)
- Ruxolitinib Impurity 53 (CAS CATO-C4X-205853)
Recommended Standards
- Thiotepa Impurity 14 (CAS CATO-C4X-215614)
- (2E,6E,10E)-1-Bromo-3,7,11,15-Tetramethylhexadeca-2,6,10,14-Tetraene (CAS 50848-64-1)
- Besudil Impurity 1 (CAS CATO-C4X-29881)
- N-Allyl-2-imino-1-(2-methoxyethyl)-5-oxo-2,5-dihydro-1H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide (CAS 371923-17-0)
- Salbutamol Impurity 101 (CAS CATO-C4X-1176101)
- Trimebutine Impurity 24 (CAS 16623-25-9)
- Siponimod impurity 20 (CAS CATO-C4X-247220)
- 1-(1-Ethyl-3-methyl-1H-pyrazol-4-yl)-N-((1-isopropyl-5-methyl-1H-pyrazol-4-yl)methyl)methanamine hydrochloride (CAS 1856083-43-6)
- 7,8-Dihydroxy-3-methylisochroman-4-one (CAS 945619-75-0)
- 4-(Aminomethyl)tetrahydrothiopyran 1,1-Dioxide (CAS 476660-77-2)
- (R)-1-(3-Fluoro-2-methylphenyl)ethanamine (CAS 1213876-59-5)
- {4-[(2,2,2-Trifluoroethoxy)methyl]phenyl}amine (CAS 923255-94-1)
- 4-{2-[(5-chloro-2-methoxyphenyl)formamido]ethyl}benzene-1-sulfonyl chloride (CAS 33924-54-8)
- Semaglutide Impurity 138 (CAS CATO-C4X-2226138)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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