Lomefloxacin Impurity 22 Trifluoroacetate CAS CATO-C4X-207322
| CAS No. | CATO-C4X-207322 |
| Molecular Formula | C17H19ClFN3O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Lomefloxacin Impurity 22 Trifluoroacetate (CAS CATO-C4X-207322, C17H19ClFN3O3C2HF3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Lomefloxacin Impurity 22 Trifluoroacetate (C17H19ClFN3O3C2HF3O2) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Lomefloxacin Impurity 22 Trifluoroacetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H19ClFN3O3 C2HF3O2 |
| Molecular Weight | 481.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Lomefloxacin Standards
- Lomefloxacin Impurity 9 (CAS 183235-15-6)
- Lomefloxacin Impurity N1 (CAS 195259-11-1)
- Lomefloxacin Impurity 4 (CAS 195259-11-1（free base）)
- Lomefloxacin Impurity 8 (CAS 195259-12-2)
- Lomefloxacin Impurity 7 (CAS 195259-19-9)
- Lomefloxacin Aspartate (CAS 211690-33-4)
- Lomefloxacin Impurity 1 (CAS 75338-42-0)
- Lomefloxacin (CAS 98079-51-7)
Recommended Standards
- Topiramate Impurity 8 (CAS 912456-61-2)
- Ivabradine Impurity 100 (CAS CATO-C4X-1119100)
- Parecoxib Impurity 34 (CAS CATO-C4X-159134)
- 2,2-Dimethyl-1-(pyrrolidin-3-yl)propan-1-one (CAS 1315591-82-2)
- Nilotinib Impurity 51 (CAS CATO-C4X-125651)
- 1-(4-Fluoro-2-nitrophenyl)-4-methylpiperidine (CAS 432523-27-8)
- 1-Methyl-1H-indole-4-carboximidamidehydrochloride (CAS 77072-12-9)
- 1,2-Benzenedicarboxylic Acid 1-(7-Hydroxy-4-methyloctyl) Ester (CAS 936021-98-6)
- Rutamarin (CAS 13164-05-1)
- Semaglutide impurity 229 (CAS CATO-C4X-2226229)
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