Lusutrombopag Impurity 2 CAS CATO-C4X-20842
| CAS No. | CATO-C4X-20842 |
| Molecular Formula | C12H10Cl2O4 |
| Molecular Weight | 289.11 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Lusutrombopag Impurity 2 (CAS CATO-C4X-20842), a pharmacopoeial impurity reference standard (molecular formula C12H10Cl2O4, MW 289.11 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C12H10Cl2O4, Lusutrombopag Impurity 2 contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 289.11 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H10Cl2O4 |
| Molecular Weight | 289.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Lusutrombopag Standards
- Lusutrombopag Impurity 84 (CAS CATO-C4X-208484)
- Lusutrombopag Impurity 22 (CAS CATO-C4X-208422)
- Lusutrombopag Impurity 47 (CAS CATO-C4X-208447)
- Lusutrombopag Impurity 26 (CAS CATO-C4X-208426)
- Lusutrombopag Impurity 21 (CAS CATO-C4X-208421)
- Lusutrombopag Impurity 29 (CAS CATO-C4X-208429)
- Lusutrombopag Impurity N3 (CAS 1110767-89-9)
- Lusutrombopag Impurity 35 (CAS CATO-C4X-208435)
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