Lusutrombopag Impurity 21 CAS CATO-C4X-208421
| CAS No. | CATO-C4X-208421 |
| Molecular Formula | C17H26O3 |
| Molecular Weight | 278.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Lusutrombopag Impurity 21 (CAS CATO-C4X-208421, C17H26O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Lusutrombopag Impurity 21 (C17H26O3) contains a steroid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H26O3 |
| Molecular Weight | 278.39 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Lusutrombopag Standards
- Lusutrombopag Impurity 29 (CAS CATO-C4X-208429)
- Lusutrombopag Impurity 26 (CAS CATO-C4X-208426)
- Lusutrombopag Impurity 22 (CAS CATO-C4X-208422)
- Lusutrombopag Impurity 35 (CAS CATO-C4X-208435)
- Lusutrombopag Impurity 2 (CAS CATO-C4X-20842)
- Lusutrombopag Impurity 84 (CAS CATO-C4X-208484)
- Lusutrombopag Impurity 3 (CAS CATO-C4X-20843)
- Lusutrombopag Impurity 70 (CAS CATO-C4X-208470)
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