Lusutrombopag Impurity 65 CAS CATO-C4X-208465
| CAS No. | CATO-C4X-208465 |
| Molecular Formula | C8H15ClO |
| Molecular Weight | 162.66 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Lusutrombopag Impurity 65 is closely related to a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Lusutrombopag Impurity 65 (CAS CATO-C4X-208465) is a certified pharmaceutical impurity reference standard with the molecular formula C8H15ClO and a molecular weight of 162.66 g/mol.
Lusutrombopag Impurity 65 (C8H15ClO) contains a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Lusutrombopag Impurity 65 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H15ClO |
| Molecular Weight | 162.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| Halogen Content | Cl-containing |
Related Lusutrombopag Standards
- Lusutrombopag Impurity N7 (CAS 13513-82-1)
- Lusutrombopag Impurity 64 (CAS CATO-C4X-208464)
- Lusutrombopag Impurity 78 (CAS CATO-C4X-208478)
- Lusutrombopag Impurity N6 (CAS 67442-07-3)
- Lusutrombopag Impurity 12 (CAS 2043804-10-8)
- Lusutrombopag Impurity 20 (CAS 30279-00-6)
- Lusutrombopag Impurity 27 (CAS CATO-C4X-208427)
- Lusutrombopag Impurity 1 (CAS 52043-45-5)
Recommended Standards
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