Nicergoline EP Impurity I CAS CATO-C4X-20859
| CAS No. | CATO-C4X-20859 |
| Molecular Formula | C46H46Br2N6O6 |
| Molecular Weight | 938.70 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 938.70 g/mol gives Nicergoline EP Impurity I distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Nicergoline EP Impurity I (CAS CATO-C4X-20859, C46H46Br2N6O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Nicergoline EP Impurity I (C46H46Br2N6O6) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Nicergoline EP Impurity I under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C46H46Br2N6O6 |
| Molecular Weight | 938.70 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 26.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 6 |
Related Nicergoline Standards
- Nicergoline EP Impurity J (CAS CATO-C4X-208510)
- Nicergoline Impurity 29 (CAS CATO-C4X-208529)
- Nicergoline Impurity 17 (CAS CATO-C4X-208517)
- Nicergoline Impurity 27 (CAS 2061916-37-6)
- Nicergoline Impurity 28 (CAS CATO-C4X-208528)
- Nicergoline-13C-d3 (CAS CATO-C4X-208513)
- Nicergoline (CAS 27848-84-6)
- Nicergoline Impurity 26 (CAS CATO-C4X-208526)
Recommended Standards
- 88847-11-4 1,2,4-Tri-O-galloyl-3,6-hexahydroxydiphenoylglucose beta-D-Glucopyranose, cyclic 3,6-(4,4',5,5',6,6')-hexahydroxy(1,1'-biphenyl)-2,2'-dicarboxylate) 1,2,4-tris(3,4,5-trihydroxybenzoate), (R)- Punicafolin (CAS 88847-11-4)
- 3-Indolepropionyl-CoA (CAS 144319-97-1)
- (11aR,13S,14R,15S,15aR)-2,3,4,5,6,7-hexahydroxy-9,17-dioxo-9,11,11a,13,14,15,15a,17-octahydrodibenzo[g,i]pyrano[3,2-b][1,5]dioxacycloundecine-13,14,15-triyl tris(3,4,5-trihydroxybenzoate) 1,2,3-trigalloyl-4,6-hexahydroxydiphenoyl beta-D-glucopyranose 58970-75-5 CHEBI:4916 Cornustannin 2 Tellimagrandin II beta-D-Glucopyranose,cyclic4,6-(4,4',5,5',6,6'-hexahydroxy(1,1'-biphenyl)-2,2'-dicarboxylate)1,2,3-tris(3,4,5-trihydroxybenzoate) eugeniin (CAS 58970-75-5)
- Neoagarohexaitol (CAS 68289-59-8)
- Pazopanib Impurity 19 (CAS 6973-09-7)
- Quinine Sulfate EP Impurity C (CAS 522-66-7)
- N-Nitroso Cimetidine impurity 25 (CAS CATO-C4X-158925)
- 5361-25-1 N-(6-Ethyl-4-methylquinazolin-2-yl)guanidine MFCD01564234 (CAS 5361-25-1)
- 5-Cyclopropyl-2-isopropylthiophen-3-amine hydrochloride (CAS 2567558-12-5)
- 3-Amino-1H-indazole-7-carbonitrile (CAS 1137451-25-2)
- Methyl 4-(2-ethoxyethoxy)thiophene-2-carboxylate (CAS 1707727-90-9)
- Lacosamide Impurity 43 (CAS 69805-82-9)
- (2-(Di-p-tolylamino)phenyl)boronic acid (CAS 1579983-01-9)
- Hepcidin/LEAP-1 (Human); Liver-Expressed Antimicrobial Peptide (CAS 342790-21-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com