Ioversol Impurity 20 CAS CATO-C4X-209120

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-209120
Molecular FormulaC18H24I3N3O8
Molecular Weight791.11 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Ioversol Impurity 20 CAS CATO-C4X-209120 chemical structure

Description

The occurrence of Ioversol Impurity 20 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Ioversol Impurity 20 (CAS CATO-C4X-209120), a pharmacopoeial impurity reference standard (molecular formula C18H24I3N3O8, MW 791.11 g/mol) used for the identification and quantification of trace impurities in APIs.

Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution, Ioversol Impurity 20 is typically off-white to pale yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 791.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Ioversol Impurity 20 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H24I3N3O8
Molecular Weight791.11 g/mol
Purity>95%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentI-containing
Nitrogen Atoms3

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