Ioversol Impurity 12 CAS 70894-76-7
| CAS No. | 70894-76-7 |
| Molecular Formula | C18H24I3N3O8 |
| Molecular Weight | 791.11 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ioversol Impurity 12.
Ioversol Impurity 12 (CAS 70894-76-7) is a certified pharmaceutical impurity reference standard with the molecular formula C18H24I3N3O8 and a molecular weight of 791.11 g/mol.
The molecular framework of Ioversol Impurity 12 (C18H24I3N3O8) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ioversol Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H24I3N3O8 |
| Molecular Weight | 791.11 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 3 |
Related Ioversol Standards
- Ioversol Impurity 18 (CAS CATO-C4X-209118)
- Ioversol Impurity 19 (CAS CATO-C4X-209119)
- Ioversol Impurity 20 (CAS CATO-C4X-209120)
- Ioversol impurity 28 (CAS CATO-C4X-209128)
- Ioversol impurity 29 (CAS CATO-C4X-209129)
- Ioversol impurity 31 (CAS CATO-C4X-209131)
- Ioversol Impurity 5 (CAS 104517-96-6)
- Ioversol (CAS 87771-40-2)
Recommended Standards
- Iopromide Impurity 23 (CAS CATO-C4X-183223)
- Iopromide (CAS 73334-07-3)
- Iopamidol Impurity 50 (CAS CATO-C4X-145050)
- Iopamidol Impurity 26 (CAS CATO-C4X-145026)
- Empagliflozin impurity 326 (CAS CATO-C4X-1065326)
- Vitamin A Impurity 21 (CAS CATO-C4X-218721)
- Linagliptin Impurity 47 (CAS 2468656-63-3)
- N-(4-Chlorophenyl)-6-methylimidazo[2,1-b][1,3]thiazole-5-carboxamide (CAS 478066-27-2)
- 3-(Thiophen-2-yl)-5-(trifluoromethyl)isoxazole (CAS 175203-89-1)
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- Hexadecane-2,15-dione (CAS 18650-13-0)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com