Ioversol impurity 28 CAS CATO-C4X-209128
| CAS No. | CATO-C4X-209128 |
| Molecular Formula | C16H19ClI3N3O7 |
| Molecular Weight | 781.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ioversol impurity 28.
CATO supplies Ioversol impurity 28 (CAS CATO-C4X-209128), a pharmacopoeial impurity reference standard (molecular formula C16H19ClI3N3O7, MW 781.50 g/mol) used for the identification and quantification of trace impurities in APIs.
Ioversol impurity 28 (C16H19ClI3N3O7) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ioversol impurity 28 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H19ClI3N3O7 |
| Molecular Weight | 781.50 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 3 |
Related Ioversol Standards
- Ioversol impurity 29 (CAS CATO-C4X-209129)
- Ioversol Impurity 12 (CAS 70894-76-7)
- Ioversol Impurity 18 (CAS CATO-C4X-209118)
- Ioversol Impurity 19 (CAS CATO-C4X-209119)
- Ioversol Impurity 20 (CAS CATO-C4X-209120)
- Ioversol Hydrolyzate(N-Desmethyl Iomeprol) (CAS 77868-40-7)
- Ioversol impurity 35 (CAS CATO-C4X-209135)
- Ioversol impurity 31 (CAS CATO-C4X-209131)
Recommended Standards
- Iodixanol Impurity 17 (CAS 77203-11-3)
- Bis-[1,3-Bis(2,4,6-trimethylphenyl)-1,3-dihydro-2H-imidazol-2-ylidene][1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]methanesulfonamidato-κN]gold (CAS 951776-25-3)
- Trihexadecyl(phenyl)silane (CAS 18822-36-1)
- CAS CATO-C3D-262838 (CAS CATO-C3D-262838)
- Neratinib Impurity 33 HCl (CAS 1259519-60-2)
- Mirabegron Impurity 27 (CAS 66659-20-9)
- Econazole impurity 30 (CAS CATO-C4X-132730)
- 1-(2-Chloro-6-fluorobenzyl)-3-(3,4-dimethoxyphenyl)-1H-pyrazole-4-carbaldehyde (CAS 1007192-89-3)
- 2-(Trifluoromethyl)quinoline-5-carboxylic acid (CAS 1260671-21-3)
- 1'-Methyl-4'-(p-tolyl)dispiro[chromane-3,3'-pyrrolidine-2',3''-indoline]-2'',4-dione (CAS 1164542-34-0)
- 4-[4-(4-Nitrophenyl)-6-phenylpyrimidin-2-yl]morpholine (CAS 352225-04-8)
- 1-Chloro-2-(difluoromethyl)-3,5-difluorobenzene (CAS 1261846-42-7)
- 4-(4,6-Dimethoxypyrimidin-2-yl)benzaldehyde (CAS 77232-34-9)
- Tetrapeptide-3 (CAS 827306-97-8)
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