Baloxavir Marboxil Impurity 221 CAS CATO-C4X-2108221
| CAS No. | CATO-C4X-2108221 |
| Molecular Formula | C27H23F2N3O9S |
| Molecular Weight | 603.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Baloxavir Marboxil Impurity 221 (CAS CATO-C4X-2108221, C27H23F2N3O9S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Baloxavir Marboxil Impurity 221 (C27H23F2N3O9S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H23F2N3O9S |
| Molecular Weight | 603.55 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Baloxavir Standards
- Baloxavir Marboxil Impurity 168 (CAS CATO-C4X-2108168)
- Baloxavir Impurity 49 (CAS CATO-C4X-210849)
- Baloxavir Impurity 76 (CAS CATO-C4X-210876)
- Baloxavir Marboxil Impurity 157 (CAS CATO-C4X-2108157)
- Baloxavir lmpurity 59 (CAS CATO-C4X-210859)
- Baloxavir Impurity 150 (CAS CATO-C4X-2108150)
- Baloxavir Impurity 153 (CAS CATO-C4X-2108153)
- Baloxavir Impurity 112 (CAS CATO-C4X-2108112)
Recommended Standards
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- (2S,3R,4S,5S,6S)-2,3,4,5-tetrakis(benzyloxy)-6-(bromomethyl)tetrahydro-2H-pyran (CAS 79774-73-5)
- 2-[(3-endo)-3-[[5-Cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-4-isoxazolyl]methoxy]-8-azabicyclo[3.2.1]octan-8-yl]-4-fluorobenzo[d]thiazole-6-carboxylic Acid (CAS 1383816-29-2)
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- Omadacycline Impurity 49 (CAS CATO-C4X-285749)
- 1-(Pyrimidin-2-yl)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea (CAS 874298-03-0)
- Vitamin K1 Impurity 44 (CAS 873964-73-9)
- tert-Butyl (5-bromo-3-cyanopyridin-2-yl)carbamate (CAS 1346532-96-4)
- <SC>L</SC>-Menthyl lactate (CAS 185915-25-7)
- 1,2,3,4,5-Pentabromo-6-(2,5-dibromophenoxy)benzene (CAS 405237-86-7)
- 1,3-Dimethoxy-1,1,2,3,3-pentafluoropropane (CAS 758-62-3)
- Peptide Impurity 81 TFA (CAS CATO-CPTD788581)
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