Gadobutrol Impurity 142 CAS CATO-C4X-2120142

Description

The occurrence of Gadobutrol Impurity 142 is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Gadobutrol Impurity 142 (CAS CATO-C4X-2120142), a pharmacopoeial impurity reference standard (molecular formula C20H40N4O10, MW 496.55 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Gadobutrol Impurity 142 (C20H40N4O10) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Gadobutrol Impurity 142 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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