Gadobutrol Impurity 144 CAS CATO-C4X-2120144

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-2120144
Molecular FormulaC20H40N4O10
Molecular Weight496.55 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Gadobutrol Impurity 144 CAS CATO-C4X-2120144 chemical structure

Description

CATO supplies Gadobutrol Impurity 144 (CAS CATO-C4X-2120144), a pharmacopoeial impurity reference standard (molecular formula C20H40N4O10, MW 496.55 g/mol) used for the identification and quantification of trace impurities in APIs.

Gadobutrol Impurity 144 (C20H40N4O10) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Gadobutrol Impurity 144 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC20H40N4O10
Molecular Weight496.55 g/mol
AppearanceWhite to pale yellow crystalline powder
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
Nitrogen Atoms4

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