Gadobutrol Impurity 182 CAS CATO-C4X-2120182
| CAS No. | CATO-C4X-2120182 |
| Molecular Formula | C18H32N4O8 |
| Molecular Weight | 432.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Gadobutrol Impurity 182 (CAS CATO-C4X-2120182), a pharmacopoeial impurity reference standard (molecular formula C18H32N4O8, MW 432.47 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Gadobutrol Impurity 182 (C18H32N4O8) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C18H32N4O8 |
| Molecular Weight | 432.47 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Gadobutrol Standards
- Gadobutrol Impurity 102 (CAS 2101625-18-5)
- Gadobutrol Impurity 123 (CAS CATO-C4X-2120123)
- Gadobutrol Impurity 188 (CAS CATO-C4X-2120188)
- Gadobutrol Impurity 101 (CAS 835640-27-2)
- Gadobutrol impurity 179 (CAS 138168-36-2)
- Gadobutrol Impurity 107 (CAS 120041-08-9)
- Gadobutrol Impurity 190 (CAS 138884-14-7)
- Gadobutrol Impurity 16 (CAS CATO-C4X-212016)
Recommended Standards
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- Formoterol impurity 128 (CAS CATO-C4X-1525128)
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- Ibandronic Impurity 15 HCl (CAS 40870-84-6 (free base))
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- Ethyl 8-chloro-6-methylimidazo[1,2-a]pyridine-2-carboxylate (CAS 1522191-12-3)
- N1-Ethyl-N3-(3-methoxypropyl)-1,3-propanediamine (CAS 1040693-27-3)
- Hexapeptide-11 (CAS 161258-30-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com