Amlexanox Impurity 3 CAS CATO-C4X-21763
| CAS No. | CATO-C4X-21763 |
| Molecular Formula | C15H17NO3 |
| Molecular Weight | 259.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Amlexanox Impurity 3 (C15H17NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Amlexanox Impurity 3 (CAS CATO-C4X-21763, C15H17NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H17NO3 |
| Molecular Weight | 259.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Amlexanox Standards
- Amlexanox Impurity 4 (CAS CATO-C4X-21764)
- Amlexanox Impurity 8 (CAS CATO-C4X-21768)
- Amlexanox (CAS 68302-57-8)
- Amlexanox Impurity 6 (CAS CATO-C4X-21766)
- Amlexanox Impurity 1 (CAS CATO-C4X-21761)
- Amlexanox Impurity 5 (CAS CATO-C4X-21765)
- Amlexanox Impurity 7 (CAS CATO-C4X-21767)
- Amlexanox Impurity 2 (CAS CATO-C4X-21762)
Recommended Standards
- Brivaracetam Impurity 84 (CAS CATO-C4X-200784)
- Velpatasvir impurity 18 (CAS CATO-C4X-289418)
- Topiramate Impurity 15 (CAS 128316-82-5)
- Velpatasvir impurity 19 (CAS CATO-C4X-289419)
- Lenalidomide Impurity 40 (CAS CATO-C4X-190340)
- Rifamycin Impurity 15 (CAS CATO-C4X-200413)
- Palonosetron Impurity 34 (CAS 1227162-74-4)
- 7-Fluoroindoline hydrochloride (CAS 1820711-83-8)
- 1-(6-Methoxypyridin-2-yl)ethan-1-ol (CAS 925417-04-5)
- Ethyl 2-(2,4-dichloro-5-(4-oxo-2-thioxo-1,4-dihydroquinazolin-3(2H)-yl)phenoxy)acetate (CAS 339015-14-4)
- 1-(5-Chlorothiophen-2-yl)-2-((2-nitropyridin-3-yl)oxy)ethan-1-one (CAS 741734-32-7)
- Cefamandole Impurity 11 (CAS CATO-C4X-122111)
- Methyl 8-bromoimidazo[1,2-a]pyrazine-2-carboxylate (CAS 2090804-28-5)
- Pancreatic Polypeptide (31-36) Free Acid, human (CAS 192432-73-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com