Amlexanox Impurity 4 CAS CATO-C4X-21764
| CAS No. | CATO-C4X-21764 |
| Molecular Formula | C16H12N2O3 |
| Molecular Weight | 280.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Amlexanox Impurity 4 (CAS CATO-C4X-21764), a pharmacopoeial impurity reference standard (molecular formula C16H12N2O3, MW 280.28 g/mol) used for the identification and quantification of trace impurities in APIs.
Amlexanox Impurity 4 (C16H12N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H12N2O3 |
| Molecular Weight | 280.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Amlexanox Standards
- Amlexanox (CAS 68302-57-8)
- Amlexanox Impurity 3 (CAS CATO-C4X-21763)
- Amlexanox Impurity 8 (CAS CATO-C4X-21768)
- Amlexanox Impurity 5 (CAS CATO-C4X-21765)
- Amlexanox Impurity 6 (CAS CATO-C4X-21766)
- Amlexanox Impurity 1 (CAS CATO-C4X-21761)
- Amlexanox Impurity 7 (CAS CATO-C4X-21767)
- Amlexanox Impurity 2 (CAS CATO-C4X-21762)
Recommended Standards
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- Perampanel Impurity 56 (CAS CATO-C4X-243056)
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- Solriamfetol Impurity 6 (CAS CATO-C4X-25636)
- (S)-Ibuprofen EP Impurity B (CAS 404354-76-3)
- Niraparib Impurity 40 (CAS CATO-C4X-232940)
- Olopatadine Impurity 20 (CAS 962-95-8)
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- Pyrimidine, 2-chloro-4-(3,4-dimethoxyphenyl)-5-fluoro- (CAS 1494526-17-8)
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- 1-(3-Aminophenyl)pyridin-1-ium chloride (CAS 117506-55-5)
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- 1-(4,5-Dichloro-2-hydroxyphenyl)ethan-1-one (CAS 22526-30-3)
- (D-Tyr1,N-Me-Phe3)-Neuropeptide FF (H-4752.0001) (CAS 145274-93-7)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com