Amlexanox CAS 68302-57-8
| CAS No. | 68302-57-8 |
| Molecular Formula | C16H14N2O4 |
| Molecular Weight | 298.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 298.29 g/mol gives Amlexanox distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Amlexanox (CAS 68302-57-8), molecular formula C16H14N2O4 and molecular weight 298.29 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Amlexanox (C16H14N2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Amlexanox meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H14N2O4 |
| Molecular Weight | 298.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Nitrogen Atoms | 2 |
Related Amlexanox Standards
- Amlexanox Impurity 4 (CAS CATO-C4X-21764)
- Amlexanox Impurity 5 (CAS CATO-C4X-21765)
- Amlexanox Impurity 3 (CAS CATO-C4X-21763)
- Amlexanox Impurity 7 (CAS CATO-C4X-21767)
- Amlexanox Impurity 8 (CAS CATO-C4X-21768)
- Amlexanox Impurity 2 (CAS CATO-C4X-21762)
- Amlexanox Impurity 6 (CAS CATO-C4X-21766)
- Amlexanox Impurity 1 (CAS CATO-C4X-21761)
Recommended Standards
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- 7-Fluoro-5-((tetrahydro-2H-pyran-4-yl)oxy)quinazolin-4-ol (CAS 379228-59-8)
- 2-Chloro-n-[3-(3,5-dimethylphenyl)-1-phenyl-1h-pyrazol-5-yl]acetamide (CAS 956713-25-0)
- 4-Bromo-2-(((4-cyclohexylphenyl)amino)methyl)-6-methoxyphenol (CAS 763130-42-3)
- 2-{4-[(Methylamino)methyl]phenoxy}benzonitrile hydrochloride (CAS 1185294-77-2)
- 3-(2,6-Dimethylphenyl)-1-phenylpropan-1-one (CAS 898754-24-0)
- Des-[Gly]31-Semaglutide(x TFA Salt) (CAS 873874-39-6(free base))
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