Fluralaner impurity 37 CAS CATO-C4X-218037
| CAS No. | CATO-C4X-218037 |
| Molecular Formula | C18H11Cl2F3O3 |
| Molecular Weight | 403.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Fluralaner impurity 37.
CATO supplies Fluralaner impurity 37 (CAS CATO-C4X-218037), a pharmacopoeial impurity reference standard (molecular formula C18H11Cl2F3O3, MW 403.18 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Fluralaner impurity 37 (C18H11Cl2F3O3) is characterized by a steroid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H11Cl2F3O3 |
| Molecular Weight | 403.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
Related Fluralaner Standards
- Fluralaner Impurity N2 (CAS 1095275-26-5)
- Fluralaner impurity 29 (CAS CATO-C4X-218029)
- Fluralaner Impurity 21 (CAS CATO-C4X-218021)
- Fluralaner Impurity 22 (CAS CATO-C4X-218022)
- Fluralaner Impurity 6 (CAS 864725-62-2)
- Fluralaner Impurity N1 (CAS 1095275-07-2)
- Fluralaner impurity 32 (CAS CATO-C4X-218032)
- Fluralaner Impurity 23 (CAS CATO-C4X-218023)
Recommended Standards
- Cytidine Diphosphate (CAS 63-38-7)
- Diquafosol Impurity 20 (CAS 2922-94-3)
- Mefatinib Impurity 8 (CAS CATO-C4X-29928)
- 6,7-Dichloro-2-(4-ethoxyphenoxy)-3-(trifluoromethyl)quinoxaline (CAS 478039-36-0)
- Amlodipine Impurity N15 (CAS 19532-97-9)
- Silodosin Impurity 18 (CAS 160969-02-8)
- Minocycline EP Impurity E (CAS 864073-42-7)
- (E)-5-oxohex-2-enoic acid (CAS 143228-86-8)
- 8-chloro-5-methoxy-quinoline-6-carboxylic acid (CAS 926270-95-3)
- 3-Methyl-5-(2,2,2-trifluoroethoxy)picolinonitrile (CAS 1257119-94-0)
- (2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-ethynyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite (CAS 615288-66-9)
- Methyl 4-(morpholine-4-carbonyl)benzoate (CAS 6724-90-9)
- 4-Bromo-1H-benzo[d]imidazole-2-carbaldehyde (CAS 1420795-07-8)
- Liraglutide Impurity 16 TFA Salt (CAS CATO-C4X-199216)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com