Lumateperone Impurity 18 CAS CATO-C4X-220118
| CAS No. | CATO-C4X-220118 |
| Molecular Formula | C14H16ClFO3 |
| Molecular Weight | 286.73 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Lumateperone Impurity 18 (CAS CATO-C4X-220118, C14H16ClFO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Lumateperone Impurity 18 (C14H16ClFO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Lumateperone Impurity 18 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H16ClFO3 |
| Molecular Weight | 286.73 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
Related Lumateperone Standards
- Lumateperone Impurity 19 (CAS CATO-C4X-220119)
- Lumateperone Impurity N4 (CAS 313369-17-4)
- Lumateperone Impurity 84 (CAS CATO-C4X-220184)
- Lumateperone Impurity N2 (CAS 313544-31-9)
- Lumateperone Impurity 66 (CAS CATO-C4X-220166)
- Lumateperone impurity 61 (CAS CATO-C4X-220161)
- Lumateperone Impurity 69 (CAS CATO-C4X-220169)
- Lumateperone Impurity 79 (CAS CATO-C4X-220179)
Recommended Standards
- Furosemide Impurity 55 (CAS 76852-02-3)
- Ethyl 6-(4-chloro-2-fluorophenyl)-6-oxohexanoate (CAS 951886-40-1)
- Tungsten dichloride (CAS 13520-76-8)
- Ethyl 6-(2-chloro-6-fluorophenyl)-6-oxohexanoate (CAS 951887-11-9)
- Canagliflozin Impurity 97 (CAS CATO-C4X-112397)
- Tofacitinib Impurity 76 (CAS CATO-C4X-107976)
- Cefcapene Impurity 13 (CAS CATO-C4X-182413)
- 4-Chloro-N-(thiophen-2-ylmethyl)benzenesulfonamide (CAS 321703-44-0)
- Rufloxacin Impurity 1 (CAS CATO-C4X-29421)
- 1’-Acetoxy Midazolam (1.0mg/ml in Acetonitrile) (CAS 59468-89-2)
- 6-Chloro-1H-indol-4-ol (CAS 1227574-98-2)
- 3-((4,6-Dimethoxypyrimidin-2-yl)oxy)-4-methoxybenzaldehyde (CAS 866154-92-9)
- 2-(2-(4-Methoxyphenyl)-2-oxoethoxy)benzamide (CAS 866019-12-7)
- Semaglutide impurity 91 (CAS CATO-C4X-222691)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com