Lumateperone Impurity 72 CAS CATO-C4X-220172
| CAS No. | CATO-C4X-220172 |
| Molecular Formula | C24H28FN3O |
| Molecular Weight | 393.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lumateperone Impurity 72.
As a process- or degradation-related impurity, Lumateperone Impurity 72 (CAS CATO-C4X-220172, C24H28FN3O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Lumateperone Impurity 72 (C24H28FN3O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Lumateperone Impurity 72 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H28FN3O |
| Molecular Weight | 393.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Lumateperone Standards
- Lumateperone (CAS 313368-91-1)
- Lumateperone Impurity 1 (CAS 313368-92-2)
- Lumateperone Impurity 2 (CAS 1576240-15-7)
- Lumateperone Impurity 3 (CAS CATO-C4X-22013)
- Lumateperone Impurity 56 (CAS CATO-C4X-220156)
- Lumateperone Impurity 33 (CAS 2117618-96-7)
- Lumateperone Impurity 50 (CAS 2117618-98-9)
- Lumateperone Impurity 18 (CAS 1469343-42-7)
Recommended Standards
- Fmoc-β-(2-thienyl)-D-Ala-OH (CAS 201532-42-5)
- H-Cys(4-methoxytrityl)-OH (CAS 177582-20-6)
- 1-(2-Pyridinyl)-4-{[5-(1,2,3-thiadiazol-4-yl)-2-thienyl]sulfonyl}piperazine (CAS 477867-54-2)
- 1-(4-Phenyl-2-thiazolyl)-1-tert-butyl-3,3-dimethyl-5-hydroxy[4,5]-bipyrazol (CAS 321998-06-5)
- Gadoxetate impurity 23 (CAS 1618674-24-0)
- Mabuterol Impurity 10 HCl (CAS CATO-C4X-145410)
- Dextromethorphan EP Impurity C (CAS 57969-05-8)
- Doxorubicin (CAS 23214-92-8)
- 2-Hydroxy-5-(trifluoromethyl)pyridine-4-acetic acid (CAS 1227580-24-6)
- 1-(2-Bromo-5-fluorobenzyl)-4-(2-((tert-butyldimethylsilyl)oxy)ethyl)piperidine (CAS 1704065-55-3)
- 6-Fluoro-3-methyl-2,3-dihydro-1H-inden-1-one (CAS 162549-02-2)
- 5-Bromo-1-fluoro-3-methoxy-2-nitrobenzene (CAS 1137869-91-0)
- For-Met-Leu-AMC (CAS 1429788-64-6)
- Tirzepatide Impurity 25 X TFA Salt (CAS CATO-C4X-324025)
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