Roxadustat Impurity 44 CAS CATO-C4X-221344
| CAS No. | CATO-C4X-221344 |
| Molecular Formula | C18H19NO5 |
| Molecular Weight | 329.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Roxadustat Impurity 44 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 329.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Roxadustat Impurity 44 (CAS CATO-C4X-221344, C18H19NO5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Roxadustat Impurity 44 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H19NO5 |
| Molecular Weight | 329.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Roxadustat Standards
- Roxadustat Impurity N4 (CAS 1421312-33-5)
- Roxadustat Impurity 23 (CAS CATO-C4X-221323)
- Roxadustat Impurity 26 (CAS 2711953-58-9)
- Roxadustat Impurity 77 (CAS CATO-C4X-221377)
- Roxadustat Impurity 78 (CAS CATO-C4X-221378)
- Roxadustat impurity 111 (CAS CATO-C4X-2213111)
- Roxadustat Impurity 90 (CAS CATO-C4X-221390)
- Roxadustat Impurity 9 (CAS 2244489-54-9)
Recommended Standards
- Pranoprofen Impurity 73 (CAS CATO-C4X-181173)
- Carbazochrome Impurity 3 (CAS CATO-C4X-22913)
- Pranoprofen Impurity 72 (CAS CATO-C4X-181172)
- Siponimod Impurity 7 (CAS 877131-37-8)
- Iguratimod Impurity 109 (CAS CATO-C4X-1826109)
- Trimetazidine impurity 33 (CAS CATO-C4X-180333)
- Mitoxantrone EP Impurity C Ditrifluoroacetate (CAS CATO-C4X-103418)
- Ilaprazole impurity 190 (CAS CATO-C4X-1130190)
- Dabigatran Impurity 130 (CAS CATO-C4X-1089130)
- 2-((1H-1,2,3-Triazol-1-yl)methyl)-5-chloroaniline (CAS 922711-45-3)
- 5-(2,3,4-Trifluorophenoxy)pentanenitrile (CAS 1443344-87-3)
- Pentafluoro-N-methylaniline (CAS 1201-02-1)
- 2,6-Dibromo-4-fluoro-3-methylaniline (CAS 1000576-72-6)
- Ephrin-A2-Selective YSA-Peptide (CAS 532441-10-4)
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