Roxadustat Impurity N4 CAS 1421312-33-5
| CAS No. | 1421312-33-5 |
| Molecular Formula | C17H12ClNO4 |
| Molecular Weight | 329.73 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Roxadustat Impurity N4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Roxadustat Impurity N4 (CAS 1421312-33-5), a pharmacopoeial impurity reference standard (molecular formula C17H12ClNO4, MW 329.73 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C17H12ClNO4, Roxadustat Impurity N4 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 329.73 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C17H12ClNO4 |
| Molecular Weight | 329.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Roxadustat Standards
- Roxadustat Impurity 23 (CAS CATO-C4X-221323)
- Roxadustat Impurity 26 (CAS 2711953-58-9)
- Roxadustat Impurity 77 (CAS CATO-C4X-221377)
- Roxadustat Impurity 78 (CAS CATO-C4X-221378)
- Roxadustat Impurity 44 (CAS CATO-C4X-221344)
- Roxadustat impurity 111 (CAS CATO-C4X-2213111)
- Roxadustat Impurity 90 (CAS CATO-C4X-221390)
- Roxadustat Impurity 9 (CAS 2244489-54-9)
Recommended Standards
- N-(2-Chloro-6-methoxycarbonylphenyl)methyl phthamide (CAS 1403483-77-1)
- (2S,3R,4S,5S,6R)-2-((6-chloro-1H-indol-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (CAS 159954-28-6)
- 6-Chloro-3-indolyl β-D-Galactopyranoside [for Biochemical Research] (CAS 138182-21-5)
- (2R,3R,4S,5S,6R)-2-((6-chloro-1H-indol-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (CAS 467214-46-6)
- Baloxavir hydrolytic impurity 88 (CAS CATO-C4X-210888)
- Finasteride Impurity 32 (CAS 51872-67-4)
- Amiodarone Impurity 34 (CAS 159980-56-0)
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- (R)-2-(6-Isopropylpyridin-2-yl)-4-phenyl-4,5-dihydrooxazole (CAS 2227390-61-4)
- 5-Acetamidothiazole-2-carboxylic acid (CAS 408535-86-4)
- 5-methyl-5-[4-(propan-2-yl)phenyl]imidazolidine-2,4-dione (CAS 208337-63-7)
- (3,4-Dihydro-2H-pyrano[2,3-b]quinolin-7-yl)(trans-4-methoxycyclohexyl)methanone (CAS 409345-31-9)
- 2-(Furan-2-yl)-2,3-dihydro-1H-benzo[d]imidazole (CAS 344417-73-8)
- Semaglutide Impurity 190 (CAS CATO-C4X-2226190)
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