Acalabrutinib Impurity 12 CAS CATO-C4X-305512
| CAS No. | CATO-C4X-305512 |
| Molecular Formula | C22H21N7O |
| Molecular Weight | 399.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Acalabrutinib Impurity 12 (C22H21N7O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 399.45 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Acalabrutinib Impurity 12 (CAS CATO-C4X-305512), a pharmacopoeial impurity reference standard (molecular formula C22H21N7O, MW 399.45 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Acalabrutinib Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H21N7O |
| Molecular Weight | 399.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 7 |
Related Acalabrutinib Standards
- Acalabrutinib Impurity 10 (CAS CATO-C4X-305510)
- Acalabrutinib Impurity 15 (CAS CATO-C4X-305515)
- Acalabrutinib Impurity 20 (CAS CATO-C4X-305520)
- Acalabrutinib Impurity 16 (CAS 2230757-50-1)
- Acalabrutinib Impurity 2 (CAS CATO-C4X-30552)
- Acalabrutinib Impurity 3 (CAS CATO-C4X-30553)
- Acalabrutinib Impurity 4 (CAS 2198380-46-8)
- Acalabrutinib Impurity 5 (CAS CATO-C4X-30555)
Recommended Standards
- N,N',N"-Tris(3-aminophenyl)-1,3,5-triazine-2,4,6-triamine (CAS 57829-21-7)
- 4-methyl-5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-((triisopropylsilyl)ethynyl)pyridine (CAS 2847093-83-6)
- Ethyl 2'-(2-benzamidoethyl)-[2,4'-bithiazole]-4-carboxylate (CAS 30760-79-3)
- benzyl 4-(N-(tert-butoxycarbonyl)sulfamoyl)piperazine-1-carboxylate (CAS 1000018-21-2)
- Palbociclib Impurity 55 (CAS CATO-C4X-112555)
- Lisinopril Impurity 14 (CAS CATO-C4X-168114)
- Ondansetron Impurity 22 (CAS CATO-C4X-139422)
- 4-Fluoropent-4-en-1-ol (CAS 180748-67-8)
- Pyrrolidine-3-carboxylic acid pyridin-2-ylamide hydrochloride (CAS 1229625-19-7)
- (2-(((5-((4-Fluorophenyl)carbamoyl)pyrimidin-2-yl)thio)methyl)-4-(trifluoromethoxy)phenyl)boronic acid (CAS 1648843-04-2)
- 2-(Trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrazine (CAS 681249-56-9)
- 4-Formyl-3-nitrobenzonitrile (CAS 90178-78-2)
- 2-(3-Aminopiperidin-1-yl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one (CAS 1708288-39-4)
- Semaglutide impurity 34 (CAS CATO-C4X-222634)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com