Avatrombopag Impurity 80 CAS CATO-C4X-223480
| CAS No. | CATO-C4X-223480 |
| Molecular Formula | C36H44Cl2N8O2S4 |
| Molecular Weight | 819.95 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Avatrombopag Impurity 80 (CAS CATO-C4X-223480, C36H44Cl2N8O2S4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C36H44Cl2N8O2S4, Avatrombopag Impurity 80 contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 819.95 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Avatrombopag Impurity 80 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C36H44Cl2N8O2S4 |
| Molecular Weight | 819.95 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 8 |
| Sulfur Atoms | 4 |
Related Avatrombopag Standards
- Avatrombopag Impurity 117 (CAS CATO-C4X-2234117)
- Avatrombopag impurity 123 (CAS CATO-C4X-2234123)
- Avatrombopag Impurity 60 (CAS CATO-C4X-223460)
- Avatrombopag Impurity 27 (CAS 3062079-49-3)
- Avatrombopag Impurity 103 (CAS CATO-C4X-2234103)
- Avatrombopag Impurity 110 (CAS CATO-C4X-2234110)
- Avatrombopag Impurity 99 (CAS CATO-C4X-223499)
- Avatrombopag Impurity 113 (CAS CATO-C4X-2234113)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com