Isosorbide Dinitrate Impurity 28 CAS CATO-C4X-223828
| CAS No. | CATO-C4X-223828 |
| Molecular Formula | C6H9NO6 |
| Molecular Weight | 191.14 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 191.14 g/mol gives Isosorbide Dinitrate Impurity 28 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Isosorbide Dinitrate Impurity 28 (CAS CATO-C4X-223828), a pharmacopoeial impurity reference standard (molecular formula C6H9NO6, MW 191.14 g/mol) used for the identification and quantification of trace impurities in APIs.
Isosorbide Dinitrate Impurity 28 (C6H9NO6) contains a carbohydrate-derived structure, an amide group. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H9NO6 |
| Molecular Weight | 191.14 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| Nitrogen Atoms | 1 |
Related Isosorbide Standards
- Isosorbide Dinitrate, Diluted EP Impurity C (CAS 16051-77-7)
- Isosorbide Dinitrate Impurity 18 (Diluted with Lactose) (CAS 16908-90-0)
- Isosorbide Dinitrate EP Impurity B (CAS 16106-20-0)
- Isosorbide Dinitrate Impurity 10 (CAS CATO-C4X-223810)
- Isosorbide Dinitrate Impurity 11 (CAS 110627-22-0)
- Isosorbide Impurity 22 (CAS 110627-23-1)
- Isosorbide Dinitrate Impurity 5 (CAS 13042-39-2)
- Isosorbide Dinitrate Impurity 6 (CAS 65940-93-4)
Recommended Standards
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- Nitrilotriacetic acid (CAS 139-13-9)
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- H-γ-Carboxy-DL-Glu-OH (CAS 56271-99-9)
- Diphenoxylate EP Impurity B (CAS 4370-12-1)
- Ivabradine impurity 76 (CAS CATO-C4X-111976)
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- tert-Butyl 3-(((benzyloxy)carbonyl)amino)pyrrolidine-1-carboxylate (CAS 325775-36-8)
- tert-Butyl 6-hydroxy-2-azabicyclo[2.2.1]heptane-2-carboxylate (CAS 207405-59-2)
- Ethyl 5-(aminocarbonyl)thiophene-2-carboxylate (CAS 1239315-91-3)
- 3-(1H-Indol-3-yl)propan-1-amine oxalate (CAS 228098-44-0)
- Dicyclohexyl(mesityl)phosphine (CAS 870703-48-3)
- D-[Phe]6-Semaglutide (CAS CATO-CPTD788633)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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