Isosorbide Dinitrate EP Impurity B CAS 16106-20-0
| CAS No. | 16106-20-0 |
| Molecular Formula | C6H9NO6 |
| Molecular Weight | 191.14 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Isosorbide Dinitrate EP Impurity B (CAS 16106-20-0, C6H9NO6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Isosorbide Dinitrate EP Impurity B (C6H9NO6) contains a carbohydrate-derived structure, an amide group. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 191.14 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Isosorbide Dinitrate EP Impurity B under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H9NO6 |
| Molecular Weight | 191.14 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 1 |
Related Isosorbide Standards
- Isosorbide Dinitrate, Diluted EP Impurity C (CAS 16051-77-7)
- Isosorbide Dinitrate Impurity 18 (Diluted with Lactose) (CAS 16908-90-0)
- Isosorbide Dinitrate Impurity 28 (CAS CATO-C4X-223828)
- Isosorbide Dinitrate Impurity 10 (CAS CATO-C4X-223810)
- Isosorbide Dinitrate Impurity 11 (CAS 110627-22-0)
- Isosorbide Impurity 22 (CAS 110627-23-1)
- Isosorbide Dinitrate Impurity 5 (CAS 13042-39-2)
- Isosorbide Dinitrate Impurity 6 (CAS 65940-93-4)
Recommended Standards
- L-Isoidide Mononitrate (Diluted with Lactose) (CAS 16908-91-1)
- 1-nitroso-1H-indazole-7-carboxylic acid (CAS CATO-C4X-249334)
- Nitrilotriacetic acid (CAS 139-13-9)
- Levodopa Impurity 14 (CAS 161940-76-7)
- Diazoxide impurity 7 (CAS CATO-C4X-19527)
- Minodronic Impurity 4 (CAS 17745-04-9)
- Metoclopramide EP Impurity H (CAS 50-86-2)
- 5-Benzylisoxazole-3-carboxylic Acid (CAS 1621018-32-3)
- 4-(1-Aminopropyl)phenolHCl (CAS 1135288-77-5)
- Terbutaline impurity 116 (CAS CATO-C4X-1183116)
- N-(2,2-Dimethoxyethyl)-4-methoxy-N-methyl-1,3-benzodioxole-5-methanamine (CAS 108261-02-5)
- 5-Phenyl-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole-1-carbothioamide (CAS 906457-69-0)
- 2-(5-Methyl-7-oxo-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)ethyl furan-2-carboxylate (CAS 866144-69-6)
- Uremic Pentapeptide (CAS 71494-20-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com