Calcium folinate Impurity 18 CAS CATO-C4X-22418
| CAS No. | CATO-C4X-22418 |
| Molecular Formula | C20H22N8O8 |
| Molecular Weight | 502.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Calcium folinate Impurity 18 (CAS CATO-C4X-22418), a pharmacopoeial impurity reference standard (molecular formula C20H22N8O8, MW 502.44 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C20H22N8O8, Calcium folinate Impurity 18 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 502.44 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Calcium folinate Impurity 18 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H22N8O8 |
| Molecular Weight | 502.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 8 |
Related Calcium Standards
- Calcium folinate Impurity 19 (CAS 77314-00-2)
- Calcium Folinate EP Impurity B (Mixture of Diastereomers) (CAS 98814-60-9)
- Calcium folinate Impurity 11 (CAS CATO-C4X-224111)
- Calcium folinate Impurity 12 (CAS 4349-43-3)
- Calcium Folinate EP Impurity A (CAS 4271-30-1)
- Calcium Folinate Hydrate (CAS 2060570-47-8)
- Calcium Folinate EP Impurity I disodium salt (CAS 133978-76-4)
- Calcium Folinate EP Impurity E calcium salt (CAS CATO-C4X-22417)
Recommended Standards
- Levofolinate Impurity 21 (CAS CATO-C4X-133521)
- Levofolinate Impurity 20 (CAS CATO-C4X-133520)
- (E)-N'-(1-(Dibenzo[b,d]thiophen-3-yl)-2,2,2-trifluoroethylidene)-2-(trifluoromethyl)benzenesulfonohydrazide (CAS 2765244-52-6)
- Levofolinate Impurity 17 (CAS CATO-C4X-133517)
- Clopidogrel Impurity 985 (CAS CATO-C4X-1029985)
- Montelukast Impurity C167 (CAS 866923-62-8)
- Arbidol impurity 45 (CAS CATO-C4X-112945)
- H-β-tBu-DL-Ala-OH (CAS 106247-35-2)
- 2,6-Bis(3-bromophenyl)-4-phenylpyridine (CAS 123291-15-6)
- (3-Ethoxypropyl)(2,2,2-trifluoroethyl)amine (CAS 1020999-75-0)
- 4-Bromo-5-chloro-2-methylbenzaldehyde (CAS 1394291-50-9)
- 7-Hydroxy-2-methyl-5-(2-oxopropyl)-4H-chromen-4-one (CAS 28955-30-8)
- pGlu-Val-Leu-Val-Ser-Pro-Ala-Phe-Tyr-Gly-Val-Val-Pro-Ala-Val-Val-Pro-Ala-Val-Gln-Pro-Gly-Tyr-Val-Ala-Ala-Thr-Arg-Gly-Ser-Leu-His-Val-Ala-Pro-Leu-Pro-Gly-Asn-Val-Pro-Tyr-Ala-Ser-His-His-Leu-Asn-Leu-Ala-Pro-Ala-Pro-Gly-Thr-Leu (CAS CATO-CPTD788763)
- Peptide 439 (CAS CATO-CPTD788439)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com