Bilastine Impurity 22 CAS CATO-C4X-225322
| CAS No. | CATO-C4X-225322 |
| Molecular Formula | C28H39N3O2 |
| Molecular Weight | 449.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Bilastine Impurity 22 (CAS CATO-C4X-225322) is a certified pharmaceutical impurity reference standard with the molecular formula C28H39N3O2 and a molecular weight of 449.63 g/mol.
The molecular framework of Bilastine Impurity 22 (C28H39N3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Bilastine Impurity 22 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C28H39N3O2 |
| Molecular Weight | 449.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Bilastine Standards
- Bilastine impurity 113 (CAS CATO-C4X-2253113)
- Bilastine Impurity 14 (CAS 2767508-98-3)
- Bilastine Impurity 23 (CAS CATO-C4X-225323)
- Bilastine Impurity 44 (CAS CATO-C4X-225344)
- Bilastine Impurity 138 (CAS CATO-C4X-2253138)
- Bilastine Impurity 19 (CAS 202189-81-9)
- Bilastine Impurity 53 (CAS CATO-C4X-225353)
- Bilastine (CAS 202189-78-4)
Recommended Standards
- N-(4-butylphenyl)-2-((2-(3-phenylthioureido)phenyl)thio)acetamide (CAS 763118-53-2)
- (E)-({1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrazol-5-yl}methylidene)[(2,6-dichlorophenyl)methoxy]amine (CAS 318958-92-8)
- L842QB22SW 156727-74-1 Benzamide, 4-((2,5-dimethyl-4-(2-propenyl)-1-piperazinyl)(3-methoxyphenyl)methyl)-N,N-diethyl-, (2S-(1(S*),2alpha,5bet))- 4-(alpha-(4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-N,N-diethylbenzamide 4-((2,5-Dimethyl-4-(2-propenyl)-1-piperazinyl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide (2S-(1(S*),2alpha,5beta))- Snc-80 UNII-L842QB22SW Snc 80 (CAS 156727-74-1)
- N-(2-chloro-5-(trifluoromethyl)phenyl)-3-(2,6-dichlorophenyl)-5-methylisoxazole-4-carboxamide (CAS 349131-13-1)
- Orforglipron Impurity 18 (CAS CATO-C4X-323418)
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- 2-chloro-4,5-dimethylthiophene-3-carboxylic acid (CAS 1261769-27-0)
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