Chlorhexidine Impurity 36 CAS CATO-C4X-225636
| CAS No. | CATO-C4X-225636 |
| Molecular Formula | C22H34ClN9O6 |
| Molecular Weight | 556.02 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Chlorhexidine Impurity 36.
CATO supplies Chlorhexidine Impurity 36 (CAS CATO-C4X-225636), a pharmacopoeial impurity reference standard (molecular formula C22H34ClN9O6, MW 556.02 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Chlorhexidine Impurity 36 (C22H34ClN9O6) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Chlorhexidine Impurity 36 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H34ClN9O6 |
| Molecular Weight | 556.02 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 9 |
Related Chlorhexidine Standards
- Chlorhexidine Impurity 24 (CAS CATO-C4X-225624)
- Chlorhexidine-d8 Dihydrochloride (CAS 1246816-96-5)
- Chlorhexidine Impurity 6 (CAS 62247-48-7)
- Chlorhexidine EP Impurity O (CAS 2508008-02-2)
- Chlorhexidine (CAS 55-56-1)
- Chlorhexidine EP Impurity M (CAS 152504-12-6)
- Chlorhexidine EP Impurity J (CAS CATO-C4X-225614)
- Chlorhexidine Impurity 18 (CAS CATO-C4X-225618)
Recommended Standards
- 3-Chloro-4,7-difluoro-N-(2-methoxy-5-(pyridin-4-yl)benzyl)-N-((1r,4r)-4-(methylamino)cyClohexyl)benzo[b]thiophene-2-carboxamide (CAS 946002-48-8)
- Encorafenib Impurity 5 (CAS CATO-C4X-32495)
- Empagliflozin Impurity 124 (CAS CATO-C4X-1065124)
- 2-[3-[5-Chloro-3-Ethyl-1,3-Dihydro-1-(3-Sulfopropyl)-6-(Trifluoromethyl)-2H-Benzimidazol-2-Ylidene]-1-Propen-1-Yl]-3-Ethyl-Benzoxazolium Inner Salt (CAS 83783-58-8)
- Semustine Impurity 1 (CAS 75219-93-1)
- Ketorolac Impurity 28 (CAS CATO-C4X-166928)
- Metaraminol Impurity N2 (CAS 693772-30-4)
- (2S,3S)-2,3-Bis(benzoyloxymethyl)cyclobutanone (CAS 132294-16-7)
- n-(3,4-Dimethoxybenzyl)-1-(pyridin-4-yl)methanamine (CAS 57342-20-8)
- Ethyl-(4-methyl-pyrimidin-2-yl)-amine (CAS 651718-69-3)
- 5-Fluoro-N-(3-hydroxyphenyl)-1H-indole-2-carboxamide (CAS 518059-66-0)
- 3-amino-2-[(3,5-dimethoxyphenyl)methyl]propan-1-ol (CAS 1020943-78-5)
- N-(3-Methylbenzyl)-2-(pyrrolidin-1-yl)ethanamine (CAS 827326-53-4)
- Retatrutide (CAS 2381089-83-2)
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