Baricitinib Impurity 132 CAS CATO-C4X-2260132
| CAS No. | CATO-C4X-2260132 |
| Molecular Formula | C16H18N8O4S |
| Molecular Weight | 418.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C16H18N8O4S, Baricitinib Impurity 132 contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 418.43 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Baricitinib Impurity 132 (CAS CATO-C4X-2260132) is a certified pharmaceutical impurity reference standard with the molecular formula C16H18N8O4S and a molecular weight of 418.43 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H18N8O4S |
| Molecular Weight | 418.43 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 8 |
| Sulfur Atoms | 1 |
Related Baricitinib Standards
- Baricitinib Impurity 26 (CAS CATO-C4X-226026)
- Baricitinib Impurity 60 (CAS CATO-C4X-226060)
- Baricitinib Impurity 53 (CAS CATO-C4X-226053)
- Baricitinib Impurity 56 (CAS CATO-C4X-226056)
- Baricitinib Impurity 55 (CAS CATO-C4X-226055)
- Baricitinib Impurity 40 (CAS CATO-C4X-226040)
- Baricitinib Impurity 101 (CAS CATO-C4X-2260101)
- Baricitinib Impurity 111 (CAS CATO-C4X-2260111)
Recommended Standards
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- 3-(4-Ethylphenyl)-2-hydroxypropanoic acid (CAS 917247-84-8)
- Methyl 3-[(2-methoxyethyl)amino]butanoate (CAS 1153454-65-9)
- 5-Chloro-2-(trifluoromethoxy)benzene-1-sulfonyl chloride (CAS 77797-64-9)
- Angelol K (CAS 169736-93-0)
- 4-Chloro-N-((3-(2-chlorophenyl)isoxazol-5-yl)methyl)benzenesulfonamide (CAS 343372-71-4)
- Tau Peptide (74-102) (Exon 3/Insert 2 Domain) trifluoroacetate salt (CAS 1322695-34-0)
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