Baricitinib Impurity 84 CAS CATO-C4X-226084
| CAS No. | CATO-C4X-226084 |
| Molecular Formula | C14H12N8O |
| Molecular Weight | 308.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Baricitinib Impurity 84 (CAS CATO-C4X-226084, C14H12N8O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Baricitinib Impurity 84 (C14H12N8O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 308.30 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Baricitinib Impurity 84 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H12N8O |
| Molecular Weight | 308.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 8 |
Related Baricitinib Standards
- Baricitinib Impurity 83 (CAS CATO-C4X-226083)
- Baricitinib Impurity 122 (CAS CATO-C4X-2260122)
- Baricitinib Impurity N2 (CAS 941685-27-4)
- Baricitinib Impurity 109 (CAS CATO-C4X-2260109)
- Baricitinib Impurity 41 (CAS CATO-C4X-226041)
- Baricitinib Impurity 42 (CAS 1146629-77-7)
- Baricitinib Impurity 110 (CAS CATO-C4X-2260110)
- Baricitinib Impurity N4 (CAS 442847-52-1)
Recommended Standards
- N-(4,6-Difluorobenzo[d]thiazol-2-yl)-1,3-dimethyl-1H-pyrazole-5-carboxamide (CAS 1013771-75-9)
- tert-Butyl 3-(2,2,2-trifluoroacetyl)-3,8-diazabicyclo[3.2.1]octane-8-carboxylate (CAS 824982-19-6)
- N-(benzyloxy)-4-nitrobenzene-1-sulfonamide (CAS 1033774-90-1)
- Tert-butyl 1-((2,2,2-trifluoroacetamido)methyl)-2-azabicyclo[2.1.1]Hexane-2-carboxylate (CAS 2252380-51-9)
- Amitriptyline EP Impurity C (CAS 72-69-5)
- Tafluprost Impurity 12 (CAS CATO-C4X-216312)
- Dapagliflozin Impurity 185 (CAS CATO-C4X-1138185)
- (S)-3-(tert-Butoxycarbonylamino)-3-(4-hydroxyphenyl)propanoic acid (CAS 499995-80-1)
- 4-Methyl-3,4-dihydroquinoxaline-1(2H)-carboxamide (CAS 102872-96-8)
- 2-(4-(Trifluoromethyl)phenyl)cyclopropane-1-carboxylic acid (CAS 2262-03-5)
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- 203524-64-5 2,4,6,6-Tetramethylpyridin-3(6H)-one DTXSID00617915 (CAS 203524-64-5)
- Valosin Peptide (VQY), porcine (CAS 99510-37-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com