Baricitinib Impurity N2 CAS 941685-27-4
| CAS No. | 941685-27-4 |
| Molecular Formula | C15H21N5OSi |
| Molecular Weight | 315.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Baricitinib Impurity N2 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 315.45 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Baricitinib Impurity N2 (CAS 941685-27-4) is a certified pharmaceutical impurity reference standard with the molecular formula C15H21N5OSi and a molecular weight of 315.45 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Baricitinib Impurity N2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H21N5OSi |
| Molecular Weight | 315.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 5 |
Related Baricitinib Standards
- Baricitinib Impurity N4 (CAS 442847-52-1)
- Baricitinib Impurity 83 (CAS CATO-C4X-226083)
- Baricitinib Impurity 84 (CAS CATO-C4X-226084)
- Baricitinib impurity 99 (CAS 894807-98-8)
- Baricitinib Impurity 122 (CAS CATO-C4X-2260122)
- Baricitinib Impurity 109 (CAS CATO-C4X-2260109)
- Baricitinib Impurity 113 (CAS 1911644-33-1)
- Baricitinib Impurity 41 (CAS CATO-C4X-226041)
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