N-Nitroso Ponatinib Metabolite Impurity 23 CAS CATO-C4X-226923
| CAS No. | CATO-C4X-226923 |
| Molecular Formula | C28H24F3N7O2 |
| Molecular Weight | 547.54 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, N-Nitroso Ponatinib Metabolite Impurity 23 (CAS CATO-C4X-226923, C28H24F3N7O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, N-Nitroso Ponatinib Metabolite Impurity 23 (C28H24F3N7O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 19.0, corresponding to approximately 19 ring(s) or double-bond equivalent(s). With a molecular weight of 547.54 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures N-Nitroso Ponatinib Metabolite Impurity 23 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C28H24F3N7O2 |
| Molecular Weight | 547.54 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 7 |
Related N Standards
- N-Nitroso Piperacillin impurity 100 (CAS CATO-C4X-1732100)
- Nitroso Perindopril EP impurity O (CAS CATO-C4X-125252)
- N-Nitroso Ripretinib (CAS CATO-C4X-30981)
- N-Nitroso Moxifloxacin Impurity 33 (CAS CATO-C4X-1074135)
- N-Nitroso Abemaciclib (CAS CATO-C4X-293722)
- N4-Nitroso Plerixafor (CAS CATO-C4X-113325)
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Recommended Standards
- Cefoperazone Impurity 57 (CAS CATO-C4X-114957)
- JWH-018 5-Pentanoic acid β-D-glucuronide (CAS 1307803-54-8)
- Cefoperazone Ring Opening Lactone (CAS CATO-C4X-114920)
- Colchicine EP Impurity D (CAS 477-29-2)
- Repaglinide EP Impurity E (CAS 147852-26-4)
- Finerenone Impurity 254 (CAS CATO-C4X-2880254)
- Choline fenofibrate Impurity 24 (CAS 51368-55-9)
- 121020-70-0 Ethyl 2-cyano-2-(1,3-dioxolan-2-yliden)acetate ethyl 2-cyano-2-(1,3-dioxolan-2-ylidene)acetate (CAS 121020-70-0)
- 1,1,1,2,2,3,3-Heptafluoro-7-iodoheptane (CAS 2967-60-4)
- (S)-1-Fluoro-3-(methylsulfinyl)benzene (CAS 209852-82-4)
- Picaridin (CAS 119515-38-7)
- Tert-butyl (2S)-2-[(1R,2S)-1-methoxy-3-[[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]amino]-2-methyl-3-oxopropyl]pyrrolidine-1-carboxylate (CAS 2088961-49-1)
- 2-Bromo-N-(2-(4-fluorophenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl)benzamide (CAS 450342-89-9)
- Peptide Impurity 40 (CAS CATO-CPTD788840)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com