Ponatinib Impurity 24【Discontinued,See C4X-22692】 CAS CATO-C4X-226924
| CAS No. | CATO-C4X-226924 |
| Molecular Formula | C13H15N3Si |
| Molecular Weight | 241.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Ponatinib Impurity 24【Discontinued,See C4X-22692】 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Ponatinib Impurity 24【Discontinued,See C4X-22692】 (CAS CATO-C4X-226924, C13H15N3Si) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Ponatinib Impurity 24【Discontinued,See C4X-22692】 (C13H15N3Si) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 241.37 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H15N3Si |
| Molecular Weight | 241.37 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Ponatinib Standards
- Ponatinib Impurity 2 (CAS CATO-C4X-22692)
- Ponatinib Impurity 41 (CAS CATO-C4X-226941)
- Ponatinib Impurity 30 (CAS CATO-C4X-226930)
- Ponatinib Impurity 52 (CAS 31719-79-6)
- Ponatinib impurity 4 (CAS 694499-26-8)
- Ponatinib Impurity 51 (CAS 94224-92-7)
- Ponatinib Impurity 50 (CAS 1781021-72-4)
- Ponatinib impurity 7 (CAS 1300690-48-5)
Recommended Standards
- butyl 1-butylpiperidine-2-carboxylate (CAS 86200-58-0)
- Dimemorfan Phosphate Impurity 3 (CAS CATO-C4X-33583)
- trans-4-(4´-n-Butylcyclohexyl)benzonitrile (CAS 61204-00-0)
- Dimemorfan Phosphate Impurity 6 (CAS CATO-C4X-33586)
- Umeclidinium impurity 27 (CAS CATO-C4X-133927)
- Losartan Impurity 28 (CAS 124750-67-0)
- Difamilast Impurity 6 (CAS 937782-01-9)
- Tert-butyl 4,10-dioxooctahydropyrazino[1,2-a][1,4]diazepine-2(1h)-carboxylate (CAS 2490697-98-6)
- [(1,2,5,6-η)-1,5-Cyclooctadiene][(1,2,3,4,5,6-η)-1,3,5-cyclooctatriene]ruthenium (CAS 42516-72-3)
- 2-(Difluoromethyl)-3-methoxy-4-methylpyridine-5-acetonitrile (CAS 1805265-70-6)
- 4-Nitrophenyl isoquinoline-3-carboxylate (CAS 143468-70-6)
- 1-(3-Bromo-5-fluorophenyl)propan-2-one (CAS 605681-34-3)
- Metoprolol Impurity 34 (CAS CATO-C4X-136734)
- Peptide 431 (CAS CATO-CPTD788431)
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