Ponatinib Impurity 36 CAS CATO-C4X-226936

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-226936
Molecular FormulaC6H4BrN3
Molecular Weight198.02 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Ponatinib Impurity 36 CAS CATO-C4X-226936 chemical structure

Description

Owing to a nitrile group, bromine substitution, an aromatic ring system, Ponatinib Impurity 36 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 198.02 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Ponatinib Impurity 36 (CAS CATO-C4X-226936) is a certified pharmaceutical impurity reference standard with the molecular formula C6H4BrN3 and a molecular weight of 198.02 g/mol.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Ponatinib Impurity 36 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC6H4BrN3
Molecular Weight198.02 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity≥95%
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentBr-containing
Nitrogen Atoms3

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