Ponatinib Impurity 32 CAS CATO-C4X-226932
| CAS No. | CATO-C4X-226932 |
| Molecular Formula | C8H5N3 |
| Molecular Weight | 143.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ponatinib Impurity 32 is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ponatinib Impurity 32 (CAS CATO-C4X-226932) is a certified pharmaceutical impurity reference standard with the molecular formula C8H5N3 and a molecular weight of 143.15 g/mol.
The molecular framework of Ponatinib Impurity 32 (C8H5N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Ponatinib Impurity 32 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5N3 |
| Molecular Weight | 143.15 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Ponatinib Standards
- Ponatinib Impurity 35 (CAS CATO-C4X-226935)
- Ponatinib Impurity 37 (CAS 2098039-04-2)
- Ponatinib Impurity 46 (CAS CATO-C4X-226946)
- Ponatinib Impurity 40 (CAS CATO-C4X-226940)
- Ponatinib Impurity 36 (CAS CATO-C4X-226936)
- Ponatinib Impurity 39 (CAS 2702457-83-6)
- Ponatinib Impurity 41 (CAS CATO-C4X-226941)
- Ponatinib Impurity 2 (CAS CATO-C4X-22692)
Recommended Standards
- Pyrrolo[1,2-c]pyrimidine-4-carbonitrile (CAS 52951-24-3)
- Pyrrolo[1,2-b]pyridazine-7-carbonitrile (CAS 74117-24-1)
- Pyrrolo[1,2-b]pyridazine-6-carbonitrile (CAS 2111074-25-8)
- Pyrazolo[1,5-a]pyridine-7-carbonitrile (CAS 319432-36-5)
- Imipenem impurity 135 (CAS CATO-C4X-1662135)
- Progesterone Impurity 59 (CAS CATO-C4X-150259)
- Emtricitabine Impurity 28 (CAS CATO-C4X-123228)
- 3,3'-(((Pyridin-3-ylmethylene)bis(oxy))bis(methylene))dipyridine (CAS 2761253-03-4)
- (E)-4-(3-hydroxyprop-1-en-1-yl)phenyl acetate (CAS 94723-93-0)
- (R)-2-(Pyridin-2-ylmethyl)piperazine (CAS 1217456-28-4)
- (2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(3,4-dimethylphenyl)methanone (CAS 898756-14-4)
- Methyl 4-(isoxazol-5-yl)benzoate (CAS 1196059-61-6)
- 4-[(E)-2-(2,4-Dichlorophenyl)ethenyl]-2-(ethylsulfanyl)-6,6-dimethyl-1,6-dihydropyrimidine (CAS 1164553-16-5)
- Sperm Peptide P10G (H-2424.0001) (CAS 137353-73-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com