Niraparib Impurity 1 CAS CATO-C4X-23291
| CAS No. | CATO-C4X-23291 |
| Molecular Formula | C11H12N2O4 |
| Molecular Weight | 236.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Niraparib Impurity 1 (CAS CATO-C4X-23291, C11H12N2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Niraparib Impurity 1 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 236.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Niraparib Impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H12N2O4 |
| Molecular Weight | 236.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Niraparib Standards
- Niraparib Impurity 34 (CAS CATO-C4X-232934)
- Niraparib Impurity 7 (E-Isomer) (CAS 68109-89-7)
- Niraparib Impurity 7 (Mixture of Isomers) (CAS 93247-79-1)
- Niraparib Impurity 31 (CAS 946076-73-9)
- Niraparib Impurity 44 (CAS 1789348-02-2)
- Niraparib Impurity 53 (CAS 1584236-54-3)
- Niraparib Impurity 4 (CAS 138229-59-1)
- Niraparib Impurity 15 (CAS CATO-C4X-232915)
Recommended Standards
- Butylphthalide Impurity 32 (CAS 33704-16-4)
- Aspirin Impurity 15 (CAS 61414-18-4)
- Terazidone Impurity 1 (CAS CATO-C4X-30541)
- Tryptophan EP Impurity E (CAS 3978-11-8)
- Doxofylline Impurity 28 (CAS 62637-09-6)
- Atorvastatin 3-Deoxy-Hept-2-Enoic Acid Sodium Salt (CAS 1105067-93-3(free base))
- Moxifloxacin Impurity 62 (CAS CATO-C4X-107462)
- EThyl 2-bromo-2-methyl-3-oxobutanoate (CAS 32116-05-5)
- 4-(1-Pyrrolidylmethyl)phenylboronic Acid (CAS 1036991-20-4)
- 1,5,8-Trihydroxy-3-methylanthracene-9,10-dione (CAS 518-80-9)
- 5-Chloro-3-iodo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazolo[4,3-d]pyrimidine (CAS 2170598-18-0)
- Atosiban Impurity 48 (CAS CATO-C4X-229348)
- 2-Bromo-5,7-dimethylbenzo[d]thiazole, 97% (CAS 1188140-58-0)
- (Pro3)-Gastric Inhibitory Polypeptide (human) trifluoroacetate salt (CAS 299898-52-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com