Exatecan Impurity 2 Methanesulfonate CAS CATO-C4X-23822
| CAS No. | CATO-C4X-23822 |
| Molecular Formula | C24H22FN3O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Exatecan Impurity 2 Methanesulfonate is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Exatecan Impurity 2 Methanesulfonate (CAS CATO-C4X-23822), a pharmacopoeial impurity reference standard (molecular formula C24H22FN3O4CH4O3S, MW 531.55 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Exatecan Impurity 2 Methanesulfonate (C24H22FN3O4CH4O3S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Exatecan Impurity 2 Methanesulfonate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H22FN3O4 CH4O3S |
| Molecular Weight | 531.55 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Exatecan Standards
- Exatecan Impurity 1 (CAS 110351-91-2)
- Exatecan mesylate (CAS 169869-90-3)
- Exatecan (CAS 171335-80-1)
- Exatecan-d5 mesylate (CAS 2819276-88-3)
- Exatecan Impurity 6 (CAS 2922852-48-8)
- Exatecan Impurity 3 Methanesulfonate (CAS 2938875-39-7；2489613-15-0（free base）)
- Exatecan Impurity 7 Mesylate (CAS 2938875-54-6)
Recommended Standards
- Ulipristal Impurity 24 (CAS CATO-C4X-191524)
- Aprepitant Impurity 6 (CAS 170902-81-5)
- Bilirubin impurity 4 (CAS CATO-C4X-15614)
- tert-Butyl 2-(4-aminophenyl)acetate (CAS 174579-31-8)
- 2-[(E)-(4-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]oxy}phenyl)methylidene]-1-hydrazinecarbothioamide (CAS 583059-55-6)
- 2-(chloromethyl)-5-(2-methylphenyl)-1,3,4-oxadiazole (CAS 36770-20-4)
- 5-(Trifluoromethyl)piperidin-2-one (CAS 50549-24-1)
- (4-Iodophenyl)methanesulfonamide (CAS 452340-78-2)
- 5-(3,4-difluorophenyl)-5-methylimidazolidine-2,4-dione (CAS 956727-88-1)
- D-Tyr10-Tirzepatide (CAS CATO-CPTD788922)
Why CATO?
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