Fluocinolone Acetonide EP Impurity I CAS CATO-C4X-23819
| CAS No. | CATO-C4X-23819 |
| Molecular Formula | C24H28F2O6 |
| Molecular Weight | 450.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Fluocinolone Acetonide EP Impurity I (CAS CATO-C4X-23819, C24H28F2O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Fluocinolone Acetonide EP Impurity I (C24H28F2O6) contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 450.47 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Fluocinolone Acetonide EP Impurity I meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H28F2O6 |
| Molecular Weight | 450.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Fluocinolone Standards
- Fluocinolone Acetonide Impurity 16 (CAS CATO-C4X-238116)
- Fluocinolone Acetonide EP Impurity D (CAS 13242-30-3)
- Fluocinolone Acetonide Impurity 42 (CAS 3793-12-2)
- Fluocinolone Acetonide Impurity 38 (CAS CATO-C4X-238138)
- Fluocinolone Acetonide Impurity 41 (CAS CATO-C4X-238141)
- Fluocinolone Acetonide EP Impurity J (CAS 1361531-95-4)
- Fluocinolone Acetonide EP Impurity K (CAS CATO-C4X-238111)
- Fluocinolone Acetonide (CAS 67-73-2)
Recommended Standards
- Diflorasone impurity 3 (CAS CATO-C4X-24803)
- Tetracycline-d6 (CAS CATO-CCHM702732)
- Riociguat EP Impurity D (CAS 625115-54-0)
- Tetracycline-d6 (CAS 2373374-42-4)
- Benzylpenicillin Impurity 52 (CAS CATO-C4X-189952)
- Cariprazine Impurity 14 (CAS 55827-50-4)
- Quetiapine EP Impurity T (CAS 5747-46-6)
- 2-Ethynyl-[1,2,4]triazolo[1,5-a]pyridine (CAS 1373338-10-3)
- 2-Methylimidazo[1,2-b]pyridazine (CAS 17412-37-2)
- 4-fluoro-3-(4-fluorophenoxymethyl)benzoic acid (CAS 1354959-72-0)
- (3R)-3-[(4-Trifluoromethylphenyl)amino]pentanamide (3R)-3-[[4-(trifluoromethyl)phenyl]amino]pentanamide (R)-3-[[4-(Trifluoromethyl)phenyl]amino]pentanamide 667937-05-5 (CAS 667937-05-5)
- 1-(3,5-Dimethoxyphenyl)ethanamine (CAS 97294-78-5)
- Ethyl 4-(2-ethoxy-2-oxoethyl)-3,5-dimethyl-1H-pyrrole-2-carboxylate (CAS 40345-42-4)
- [Glu]17-Liraglutide (CAS CATO-C4X-199236)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com