Opicapone Impurity 8 HCl CAS CATO-C4X-240489
| CAS No. | CATO-C4X-240489 |
| Molecular Formula | C8H9Cl2N3O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Opicapone Impurity 8 HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Opicapone Impurity 8 HCl (CAS CATO-C4X-240489), a pharmacopoeial impurity reference standard (molecular formula C8H9Cl2N3OHCl, MW 270.54 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Opicapone Impurity 8 HCl is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 270.54 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C8H9Cl2N3O HCl |
| Molecular Weight | 270.54 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Opicapone Standards
- Opicapone Impurity N1 (CAS 1391712-50-7)
- Opicapone Impurity 42 (CAS 1402714-38-8)
- Opicapone Impurity N3 (CAS 1402714-41-3)
- Opicapone Impurity 83 (CAS 1428009-74-8)
- Opicapone impurity 35 (CAS 1443319-15-0)
- Opicapone impurity 66 (CAS 1639373-19-5)
- Opicapone Impurity 01 (CAS 175204-44-1)
- Opicapone impurity 21 (CAS 1962082-05-8)
Recommended Standards
- Amlodipine Impurity N5 (CAS 107812-86-2)
- Atogepant Impurity 44 (CAS CATO-C4X-328544)
- Meropenem Impurity 55 (CAS CATO-C4X-130955)
- N-Cyclopropyl-4-methoxyaniline (CAS 263244-95-7)
- 3,5,6-trichloro-2-hydroxybenzoic acid (CAS 40932-60-3)
- Pyrrolidin-2-ol (CAS 67318-87-0)
- 3-(4-Chlorophenyl)-2-cyanopropionic Acid (CAS 55502-59-5)
- 3-(1,3-Dioxan-2-yl)-1-(3-fluorophenyl)propan-1-one (CAS 898786-00-0)
- 2-(2-Fluorophenoxy)benzoic Acid (CAS 2795-61-1)
- Semaglutide Impurity 189 (CAS CATO-C4X-2226189)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com