Upadacitinib Impurity 197 CAS CATO-C4X-2405197
| CAS No. | CATO-C4X-2405197 |
| Molecular Formula | C18H20N4O4S |
| Molecular Weight | 388.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Upadacitinib Impurity 197 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Upadacitinib Impurity 197 (CAS CATO-C4X-2405197, C18H20N4O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Upadacitinib Impurity 197 (C18H20N4O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C18H20N4O4S |
| Molecular Weight | 388.44 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Upadacitinib Standards
- Upadacitinib Impurity 15 (CAS 1201187-44-1)
- Upadacitinib Impurity 118 (CAS CATO-C4X-2405118)
- Upadacitinib Impurity 12 (CAS 2095311-51-4)
- Upadacitinib Impurity 8 (CAS CATO-C4X-24058)
- Upadacitinib Impurity 95 (CAS CATO-C4X-240595)
- (±)-Upadacitinib (CAS 1831899-72-9)
- Upadacitinib Impurity 128 (CAS CATO-C4X-2405128)
- Upadacitinib-15N-d2 (CAS CATO-C4X-240579)
Recommended Standards
- Febantel EP Impurity A (CAS 92088-58-9)
- Safinamide Impurity 66 (CAS CATO-C4X-159066)
- Febantel Impurity 6 (CAS CATO-C4X-29065)
- Safinamide Impurity 60 (CAS CATO-C4X-159060)
- Apalutamide Impurity 56 (CAS CATO-C4X-274956)
- Difelikefalin Impurity 33 (CAS CATO-C4X-304133)
- Rosuvastatin Impurity 100 (CAS CATO-C4X-1169100)
- 1-Amino-6,7,8,9-tetrahydrothieno[2,3-c]isoquinoline-2-carboxamide (CAS 155412-95-6)
- 2-(Pyrrolidin-2-yl)-1-(thiophen-3-yl)ethan-1-one (CAS 1540614-07-0)
- 4-Piperidinyl 2-methoxyacetate hydrochloride (CAS 1220031-63-9)
- 4-Methyl-2-oxo-2H-chromen-7-yl methanesulfonate (CAS 62113-92-2)
- N-cyclohexyl-4-((3,4-dichloro-1-methyl-1H-pyrazol-5-yl)oxy)benzenesulfonamide (CAS 318284-25-2)
- 1,1-dimethyl 2-ethynylcyclopropane-1,1-dicarboxylate (CAS 813458-58-1)
- Semaglutide impurity 91 (CAS CATO-C4X-222691)
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