Upadacitinib Impurity 128 CAS CATO-C4X-2405128
| CAS No. | CATO-C4X-2405128 |
| Molecular Formula | C15H11F3N4O3S |
| Molecular Weight | 384.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, Upadacitinib Impurity 128 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 384.33 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Upadacitinib Impurity 128 (CAS CATO-C4X-2405128), a pharmacopoeial impurity reference standard (molecular formula C15H11F3N4O3S, MW 384.33 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H11F3N4O3S |
| Molecular Weight | 384.33 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Upadacitinib Standards
- Upadacitinib-15N-d2 (CAS CATO-C4X-240579)
- Upadacitinib (CAS 1310726-60-3)
- Upadacitinib Impurity 144 (CAS CATO-C4X-2405144)
- Upadacitinib Impurity 20 (CAS CATO-C4X-240520)
- Upadacitinib Impurity 22 (CAS CATO-C4X-240522)
- Upadacitinib Impurity 26 (CAS CATO-C4X-240526)
- Upadacitinib Impurity 28 (CAS 1310726-59-0)
- Upadacitinib Impurity 15 (CAS 1201187-44-1)
Recommended Standards
- Tetramethyl 2,6-dihydroxybicyclo[3.3.1]nona-2,6-diene-1,3,5,7-tetracarboxylate (CAS 6966-22-9)
- Eleutheroside B1 (CAS 16845-16-2)
- tert-Butyl((4-iodonaphthalen-1-yl)oxy)dimethylsilane (CAS 402476-01-1)
- Boc-d-dab(dnp)-oh (CAS 1263045-90-4)
- N-Nitroso Isoprenaline Impurity 35 (CAS CATO-C4X-277535)
- Difelikefalin Impurity 20 (CAS CATO-C4X-304120)
- Citalopram EP Impurity M HBr (CAS CATO-C4X-110946)
- 3-Oxo-3-phenyl-2-(triphenylphosphoranylidene)propanenitrile (CAS 5032-98-4)
- Hexanedioic acid, polymer with 1,3-diisocyanatomethylbenzene and 2,2'-oxybis[ethanol] (CAS 9017-08-7)
- 1-Methoxy-4-((vinyloxy)methyl)benzene (CAS 108388-36-9)
- (3'-Fluoro-[1,1'-biphenyl]-4-yl)(methyl)sulfane (CAS 1214374-74-9)
- [2-D-histidine]Deslorelin (CAS CATO-CPTD788647)
- 2-(Cyclohex-1-en-1-ylamino)benzoic acid (CAS 913255-26-2)
- [3-31]-Semaglutide D (CAS C152H230N42O47)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com